Research progress of Müller cells and retinal nerve regeneration

Retinal degenerative diseases, a type of blinding eye diseases in which retinal neuron apoptosis is the main pathological process. Neuronal cells cannot be regenerated after damage, Müller cells are important glial cells of the retina and involved in retinal development, damage, and regeneration pro...

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Main Authors: Xi-Yu Jia, Shi-Han Lan, Ting Shan, He-Jiang Ye, Jie Chen
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-02-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2021/2/202102009.pdf
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author Xi-Yu Jia
Shi-Han Lan
Ting Shan
He-Jiang Ye
Jie Chen
author_facet Xi-Yu Jia
Shi-Han Lan
Ting Shan
He-Jiang Ye
Jie Chen
author_sort Xi-Yu Jia
collection DOAJ
description Retinal degenerative diseases, a type of blinding eye diseases in which retinal neuron apoptosis is the main pathological process. Neuronal cells cannot be regenerated after damage, Müller cells are important glial cells of the retina and involved in retinal development, damage, and regeneration process. In recent years, studies have proved that Müller cells are an endogenous alternative source for stimulating damaged retinal neurons and an excellent target for retinal nerve regeneration. This article reviews the related factors of Müller cells and retinal nerve regeneration, and provides a new direction for nerve regeneration research.
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spelling doaj.art-d0ec8ac550ff4b86962a5fadf60d381d2022-12-21T19:00:22ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232021-02-0121224024310.3980/j.issn.1672-5123.2021.2.09202102009Research progress of Müller cells and retinal nerve regenerationXi-Yu Jia0Shi-Han Lan1Ting Shan2He-Jiang Ye3Jie Chen4Chengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province,China; Department of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, ChinaChengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province,China; Department of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, ChinaChengdu University of Traditional Chinese Medicine, Chengdu 610072, Sichuan Province,China; Department of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, ChinaDepartment of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, ChinaDepartment of Ophthalmology, Affiliated Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, Sichuan Province, ChinaRetinal degenerative diseases, a type of blinding eye diseases in which retinal neuron apoptosis is the main pathological process. Neuronal cells cannot be regenerated after damage, Müller cells are important glial cells of the retina and involved in retinal development, damage, and regeneration process. In recent years, studies have proved that Müller cells are an endogenous alternative source for stimulating damaged retinal neurons and an excellent target for retinal nerve regeneration. This article reviews the related factors of Müller cells and retinal nerve regeneration, and provides a new direction for nerve regeneration research.http://ies.ijo.cn/cn_publish/2021/2/202102009.pdfretinal degenerativeglial cellsmüller cellsnerve regenerationretinal neurons
spellingShingle Xi-Yu Jia
Shi-Han Lan
Ting Shan
He-Jiang Ye
Jie Chen
Research progress of Müller cells and retinal nerve regeneration
Guoji Yanke Zazhi
retinal degenerative
glial cells
müller cells
nerve regeneration
retinal neurons
title Research progress of Müller cells and retinal nerve regeneration
title_full Research progress of Müller cells and retinal nerve regeneration
title_fullStr Research progress of Müller cells and retinal nerve regeneration
title_full_unstemmed Research progress of Müller cells and retinal nerve regeneration
title_short Research progress of Müller cells and retinal nerve regeneration
title_sort research progress of muller cells and retinal nerve regeneration
topic retinal degenerative
glial cells
müller cells
nerve regeneration
retinal neurons
url http://ies.ijo.cn/cn_publish/2021/2/202102009.pdf
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AT shihanlan researchprogressofmullercellsandretinalnerveregeneration
AT tingshan researchprogressofmullercellsandretinalnerveregeneration
AT hejiangye researchprogressofmullercellsandretinalnerveregeneration
AT jiechen researchprogressofmullercellsandretinalnerveregeneration