Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach

Summary:. Hyaluronic acid fillers are one of the most widely used and versatile fillers worldwide. Although traditionally regarded as immunologically inert, many currently available products have been substantially modified to improve longevity and to optimize properties for specific indications. Su...

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Main Author: David K. Funt, MD, FACS
Format: Article
Language:English
Published: Wolters Kluwer 2022-06-01
Series:Plastic and Reconstructive Surgery, Global Open
Online Access:http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000004362
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author David K. Funt, MD, FACS
author_facet David K. Funt, MD, FACS
author_sort David K. Funt, MD, FACS
collection DOAJ
description Summary:. Hyaluronic acid fillers are one of the most widely used and versatile fillers worldwide. Although traditionally regarded as immunologically inert, many currently available products have been substantially modified to improve longevity and to optimize properties for specific indications. Such modifications, either alone or in combination with other factors (such as the immune status of the patient, immune-triggering events, and bacterial contamination), may lead to the development of late-onset inflammatory nodules in some patients. This article discusses the clinical presentation of late-onset adverse inflammatory reactions to hyaluronic acid injections, describes their likely triggers, and presents the author’s treatment algorithm for successful resolution.
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spelling doaj.art-d0ee05a3bb0240a68d1a41b00c8e23272022-12-22T00:19:55ZengWolters KluwerPlastic and Reconstructive Surgery, Global Open2169-75742022-06-01106e436210.1097/GOX.0000000000004362202206000-00042Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic ApproachDavid K. Funt, MD, FACS0From the Division of Surgery, Department of Plastic Surgery, Icahn School of Medicine, Mount Sinai Hospital, New York, N.Y.Summary:. Hyaluronic acid fillers are one of the most widely used and versatile fillers worldwide. Although traditionally regarded as immunologically inert, many currently available products have been substantially modified to improve longevity and to optimize properties for specific indications. Such modifications, either alone or in combination with other factors (such as the immune status of the patient, immune-triggering events, and bacterial contamination), may lead to the development of late-onset inflammatory nodules in some patients. This article discusses the clinical presentation of late-onset adverse inflammatory reactions to hyaluronic acid injections, describes their likely triggers, and presents the author’s treatment algorithm for successful resolution.http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000004362
spellingShingle David K. Funt, MD, FACS
Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
Plastic and Reconstructive Surgery, Global Open
title Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
title_full Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
title_fullStr Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
title_full_unstemmed Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
title_short Treatment of Delayed-onset Inflammatory Reactions to Hyaluronic Acid Filler: An Algorithmic Approach
title_sort treatment of delayed onset inflammatory reactions to hyaluronic acid filler an algorithmic approach
url http://journals.lww.com/prsgo/fulltext/10.1097/GOX.0000000000004362
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