Penicilazaphilone C, a New Azaphilone, Induces Apoptosis in Gastric Cancer by Blocking the Notch Signaling Pathway

Penicilazaphilone C, a New Azaphilone, Induces Apoptosis in Gastric Cancer by Blocking the Notch Signaling Pathway

Penicilazaphilone C (PAC) is a novel azaphilonidal derivative isolated by our group that demonstrates good anticancer activities. Considering that its molecular mechanisms remain largely unknown, here we explore the molecular mechanisms of the anticancer activities of PAC against gastric cancer. The...

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Bibliographic Details
Main Authors: Ming Wang, Huange Zhao, Juanjuan Hu, Zhen Xu, Yingying Lin, Songlin Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Oncology
Subjects:
penicilazaphilone C
notch signaling pathway
gastric cancer
apoptosis
molecular mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00116/full

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