The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates.

The adjuvanticity of an O. volvulus-derived rOv-ASP-1 protein in mice using sequential vaccinations and in non-human primates.

Adjuvants potentiate antigen-specific protective immune responses and can be key elements promoting vaccine effectiveness. We previously reported that the Onchocerca volvulus recombinant protein rOv-ASP-1 can induce activation and maturation of naïve human DCs and therefore could be used as an innat...

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Bibliographic Details
Main Authors: Jing Wang, Nancy Tricoche, Lanying Du, Meredith Hunter, Bin Zhan, Gaddam Goud, Elizabeth S Didier, Jing Liu, Lu Lu, Preston A Marx, Shibo Jiang, Sara Lustigman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3355165?pdf=render

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