Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet
<i>Bombyx mori</i> is a model lepidopteran insect of great economic value. Mulberry leaves are its only natural food source. The development of artificial diets can not only resolve the seasonal shortage of mulberry leaves but also enable changes to be made to the feed composition accord...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Insects |
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| Online Access: | https://www.mdpi.com/2075-4450/14/4/347 |
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| author | Juan Li Jing Deng Xuan Deng Lianlian Liu Xingfu Zha |
| author_facet | Juan Li Jing Deng Xuan Deng Lianlian Liu Xingfu Zha |
| author_sort | Juan Li |
| collection | DOAJ |
| description | <i>Bombyx mori</i> is a model lepidopteran insect of great economic value. Mulberry leaves are its only natural food source. The development of artificial diets can not only resolve the seasonal shortage of mulberry leaves but also enable changes to be made to the feed composition according to need. Metabolomic differences between the midguts of male and female silkworms fed either on fresh mulberry leaves or an artificial diet were studied using liquid chromatography–mass spectrography (LC-MS/MS) analysis. A total of 758 differential metabolites were identified. Our analysis showed that they were mainly involved in disease resistance and immunity, silk quality, and silkworm growth and development. These experimental results provide insights into the formulation of optimized artificial feed for silkworms. |
| first_indexed | 2024-03-11T04:54:27Z |
| format | Article |
| id | doaj.art-d0fc0fbdeed04ad0b612370fd2faef3d |
| institution | Directory Open Access Journal |
| issn | 2075-4450 |
| language | English |
| last_indexed | 2024-03-11T04:54:27Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Insects |
| spelling | doaj.art-d0fc0fbdeed04ad0b612370fd2faef3d2023-11-17T19:46:15ZengMDPI AGInsects2075-44502023-03-0114434710.3390/insects14040347Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf DietJuan Li0Jing Deng1Xuan Deng2Lianlian Liu3Xingfu Zha4State Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, ChinaState Key Laboratory of Silkworm Genome Biology, Institute of Sericulture and Systems Biology, College of Sericulture, Textile and Biomass Sciences, Southwest University, Chongqing 400715, China<i>Bombyx mori</i> is a model lepidopteran insect of great economic value. Mulberry leaves are its only natural food source. The development of artificial diets can not only resolve the seasonal shortage of mulberry leaves but also enable changes to be made to the feed composition according to need. Metabolomic differences between the midguts of male and female silkworms fed either on fresh mulberry leaves or an artificial diet were studied using liquid chromatography–mass spectrography (LC-MS/MS) analysis. A total of 758 differential metabolites were identified. Our analysis showed that they were mainly involved in disease resistance and immunity, silk quality, and silkworm growth and development. These experimental results provide insights into the formulation of optimized artificial feed for silkworms.https://www.mdpi.com/2075-4450/14/4/347artificial dietsilkwormmidgutmulberry leafmetabolomics |
| spellingShingle | Juan Li Jing Deng Xuan Deng Lianlian Liu Xingfu Zha Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet Insects artificial diet silkworm midgut mulberry leaf metabolomics |
| title | Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet |
| title_full | Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet |
| title_fullStr | Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet |
| title_full_unstemmed | Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet |
| title_short | Metabonomic Analysis of Silkworm Midgut Reveals Differences between the Physiological Effects of an Artificial and Mulberry Leaf Diet |
| title_sort | metabonomic analysis of silkworm midgut reveals differences between the physiological effects of an artificial and mulberry leaf diet |
| topic | artificial diet silkworm midgut mulberry leaf metabolomics |
| url | https://www.mdpi.com/2075-4450/14/4/347 |
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