Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy

Despite the recognized benefits of the COVID-19 vaccination, vaccine hesitancy (VH) remains one of the biggest challenges of the mass vaccination campaign. Most studies investigating VH determinants focused on socio-demographics and direct relationships. In this study, we aimed at: 1) identifying su...

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Main Authors: Elisa Maietti, Chiara Reno, Francesco Sanmarchi, Marco Montalti, Maria Pia Fantini, Davide Gori
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2022.2157622
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author Elisa Maietti
Chiara Reno
Francesco Sanmarchi
Marco Montalti
Maria Pia Fantini
Davide Gori
author_facet Elisa Maietti
Chiara Reno
Francesco Sanmarchi
Marco Montalti
Maria Pia Fantini
Davide Gori
author_sort Elisa Maietti
collection DOAJ
description Despite the recognized benefits of the COVID-19 vaccination, vaccine hesitancy (VH) remains one of the biggest challenges of the mass vaccination campaign. Most studies investigating VH determinants focused on socio-demographics and direct relationships. In this study, we aimed at: 1) identifying subgroups of people differently affected by the pandemic, in terms of psychological status; 2) investigating the role of psychological status and trust in information as possible mediators of the relationship between individual characteristics and VH. To this purpose, a latent class analysis (LCA) followed by a mediation analysis were carried out on data from a survey conducted in January 2021 on 1011 Italian citizens. LCA identified four different subgroups characterized by a differential psychological impact of the pandemic: the extremely affected (21.1%), the highly affected (49.1%), the moderately affected (21.8%) and the slightly affected (8%). We found that VH decreased with the increase of psychological impact (from 59.3% to 23.9%). In the mediation analysis, past vaccination refusal, age 45-54 years and lower-than-average income, were all indirectly related to higher VH through mistrust in COVID-19 information. Differently, the psychological impact counteracted the greater VH in females, the negative effect of social media among youngest (<35 years) and the negative effect of mistrust in the lower-than-average-income subgroup. Knowledge of psychological profile of hesitant individuals, their level of trust and the sources of information they access, together with their sociodemographic characteristics provides a more comprehensive picture of VH determinants that can be used by public health stakeholders to effectively design and adapt communication campaigns.
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spelling doaj.art-d0fc6b62a5b440f78806edbe9949819f2023-09-26T13:25:47ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2022-12-0118710.1080/21645515.2022.21576222157622Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in ItalyElisa Maietti0Chiara Reno1Francesco Sanmarchi2Marco Montalti3Maria Pia Fantini4Davide Gori5Alma Mater Studiorum – Università di BolognaAlma Mater Studiorum – Università di BolognaAlma Mater Studiorum – Università di BolognaAlma Mater Studiorum – Università di BolognaAlma Mater Studiorum – Università di BolognaAlma Mater Studiorum – Università di BolognaDespite the recognized benefits of the COVID-19 vaccination, vaccine hesitancy (VH) remains one of the biggest challenges of the mass vaccination campaign. Most studies investigating VH determinants focused on socio-demographics and direct relationships. In this study, we aimed at: 1) identifying subgroups of people differently affected by the pandemic, in terms of psychological status; 2) investigating the role of psychological status and trust in information as possible mediators of the relationship between individual characteristics and VH. To this purpose, a latent class analysis (LCA) followed by a mediation analysis were carried out on data from a survey conducted in January 2021 on 1011 Italian citizens. LCA identified four different subgroups characterized by a differential psychological impact of the pandemic: the extremely affected (21.1%), the highly affected (49.1%), the moderately affected (21.8%) and the slightly affected (8%). We found that VH decreased with the increase of psychological impact (from 59.3% to 23.9%). In the mediation analysis, past vaccination refusal, age 45-54 years and lower-than-average income, were all indirectly related to higher VH through mistrust in COVID-19 information. Differently, the psychological impact counteracted the greater VH in females, the negative effect of social media among youngest (<35 years) and the negative effect of mistrust in the lower-than-average-income subgroup. Knowledge of psychological profile of hesitant individuals, their level of trust and the sources of information they access, together with their sociodemographic characteristics provides a more comprehensive picture of VH determinants that can be used by public health stakeholders to effectively design and adapt communication campaigns.http://dx.doi.org/10.1080/21645515.2022.2157622covid-19vaccine hesitancypsychological impacttrustmediation modellatent class analysis
spellingShingle Elisa Maietti
Chiara Reno
Francesco Sanmarchi
Marco Montalti
Maria Pia Fantini
Davide Gori
Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
Human Vaccines & Immunotherapeutics
covid-19
vaccine hesitancy
psychological impact
trust
mediation model
latent class analysis
title Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
title_full Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
title_fullStr Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
title_full_unstemmed Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
title_short Are psychological status and trust in information related to vaccine hesitancy during COVID-19 pandemic? A latent class and mediation analyses in Italy
title_sort are psychological status and trust in information related to vaccine hesitancy during covid 19 pandemic a latent class and mediation analyses in italy
topic covid-19
vaccine hesitancy
psychological impact
trust
mediation model
latent class analysis
url http://dx.doi.org/10.1080/21645515.2022.2157622
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