A Novel Subunit Vaccine Based on Outer Capsid Proteins of Grass Carp Reovirus (GCRV) Provides Protective Immunity against GCRV Infection in Rare Minnow (<i>Gobiocypris rarus</i>)

A Novel Subunit Vaccine Based on Outer Capsid Proteins of Grass Carp Reovirus (GCRV) Provides Protective Immunity against GCRV Infection in Rare Minnow (<i>Gobiocypris rarus</i>)

The grass carp hemorrhagic disease, caused by the grass carp reovirus (GCRV), has resulted in severe economic losses in the aquaculture industry in China. VP4 and VP35 are outer capsid proteins of GCRV and can induce an immune response in the host. Here, three recombinant baculoviruses, AcMNPV-VP35,...

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Bibliographic Details
Main Authors: Changyong Mu, Vikram N. Vakharia, Yong Zhou, Nan Jiang, Wenzhi Liu, Yan Meng, Yiqun Li, Mingyang Xue, Jieming Zhang, Lingbing Zeng, Qiwang Zhong, Yuding Fan
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Pathogens
Subjects:
grass carp reovirus
baculovirus expression system
subunit vaccine
immune response
Online Access:https://www.mdpi.com/2076-0817/9/11/945

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