Dietary rescue of lipotoxicity-induced mitochondrial damage in Peroxin19 mutants.

Dietary rescue of lipotoxicity-induced mitochondrial damage in Peroxin19 mutants.

Mutations in peroxin (PEX) genes lead to loss of peroxisomes, resulting in the formation of peroxisomal biogenesis disorders (PBDs) and early lethality. Studying PBDs and their animal models has greatly contributed to our current knowledge about peroxisomal functions. Very-long-chain fatty acid (VLC...

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Main Authors: Julia Sellin, Christian Wingen, Dominic Gosejacob, Deniz Senyilmaz, Lea Hänschke, Sven Büttner, Katharina Meyer, Daniele Bano, Pierluigi Nicotera, Aurelio A Teleman, Margret H Bülow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2004893

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