Improving PacBio long read accuracy by short read alignment.
The recent development of third generation sequencing (TGS) generates much longer reads than second generation sequencing (SGS) and thus provides a chance to solve problems that are difficult to study through SGS alone. However, higher raw read error rates are an intrinsic drawback in most TGS techn...
| Main Authors: | , , , |
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| 格式: | 文件 |
| 语言: | English |
| 出版: |
Public Library of Science (PLoS)
2012-01-01
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| 丛编: | PLoS ONE |
| 在线阅读: | http://europepmc.org/articles/PMC3464235?pdf=render |