Synthesis, characterization and utilization of a new series of 1,2,3-triazole derivatives to neutralize some toxic activities of Bothrops jararaca snake venom

Synthesis, characterization and utilization of a new series of 1,2,3-triazole derivatives to neutralize some toxic activities of Bothrops jararaca snake venom

Abstract Snake envenomation is a public health problem, and while serum therapy prevents death, the local effects of venoms can lead to amputations or morbidities. Thus, alternative treatments deserve attention. In this study, we tested eight derivatives of 1,2,3-triazole against some toxic activiti...

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Bibliographic Details
Main Authors: Nayanna de Mello Amorim, Luiz Carlos Simas Pereira Junior, Eladio Flores Sanchez, Gabriel Alves de Aquino, Vitor Francisco Ferreira, Sabrina Baptista Ferreira, André Lopes Fuly, Eduardo Coriolano de Oliveira
Format: Article
Language:English
Published: Universidade de São Paulo 2023-01-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
1,2,3-triazole derivatives. Organic synthesis. Bothrops jararaca. Snake venom. Neutralization. Antivenom
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100831&tlng=en

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