A rare case of juxtacortic chondromyxoid fibroma in proximal humerus
Background: Chondromyxoid fibroma (CMF) is a very rare case usually appears around the knee. CMF presented high recurrence rate 25% among treated cases. However, in this case, interestingly CMF in the right upper arm was radiologically and pathologically diagnosed. It measures a 6.9 mm × 1.7 mm lesi...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-06-01
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| Series: | Translational Research in Anatomy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214854X20300054 |
| _version_ | 1818035708072296448 |
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| author | Murad Alahdal Yaoxi Li Gaorui Cai Li Duan Daping Wang |
| author_facet | Murad Alahdal Yaoxi Li Gaorui Cai Li Duan Daping Wang |
| author_sort | Murad Alahdal |
| collection | DOAJ |
| description | Background: Chondromyxoid fibroma (CMF) is a very rare case usually appears around the knee. CMF presented high recurrence rate 25% among treated cases. However, in this case, interestingly CMF in the right upper arm was radiologically and pathologically diagnosed. It measures a 6.9 mm × 1.7 mm lesion. Case presentation: 36-year-old male showed CMF in the juxtacortic proximal humerus. Computed tomography (CT) and magnetic resonance imaging (MRI) of the right upper arm interestingly presented an expansile, mildly lobulated, septate lesion a 6.9 mm × 1.7 mm. Pathological analysis of biopsy showed a bony tissue consisting of cartilaginous, fibrous and myxoid stroma with abundant stellate shaped cells that present vary nucleus size and a minority of nuclear division. Surgical allogeneic bone graft and plate internal fixation was performed after the intralesional curettage surgery. Postoperation the patient was received doxorubicin 50–75 mg/m2 21 days cycle. Results showed that the intralesional curettage surgery of CMF, allogeneic bone graft and plate internal fixation combined with doxorubicin was successfully treated CMF and efficiently prevent relapse during 20 months of observations. Conclusion: the juxtacortic CMF was unusually diagnosed in the proximal humerus, it has been efficiently eliminated by a surgical operation and doxorubicin 50–75 mg/m2 that prevented tumor recurrence. Keywords: Chondromyxoid fibroma, Juxtacortic, Proximal humerus, Bone fibroma |
| first_indexed | 2024-12-10T06:59:21Z |
| format | Article |
| id | doaj.art-d10d400855494af1926276a718e366ae |
| institution | Directory Open Access Journal |
| issn | 2214-854X |
| language | English |
| last_indexed | 2024-12-10T06:59:21Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Translational Research in Anatomy |
| spelling | doaj.art-d10d400855494af1926276a718e366ae2022-12-22T01:58:22ZengElsevierTranslational Research in Anatomy2214-854X2020-06-0119A rare case of juxtacortic chondromyxoid fibroma in proximal humerusMurad Alahdal0Yaoxi Li1Gaorui Cai2Li Duan3Daping Wang4Shenzhen Key Laboratory of Tissue Engineering, Shenzhen Laboratory of Digital Orthopedic Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University, Health Science Center), Shenzhen, 518035, PR China; Guangdong Provincial Research Center for Artificial Intelligence and Digital Orthopedic Technology, Shenzhen, 518035, PR China; Medical Laboratory Department, Faculty of Medicine and Health Sciences, Hodeidah University, Al Hudaydah, YemenShenzhen Key Laboratory of Tissue Engineering, Shenzhen Laboratory of Digital Orthopedic Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University, Health Science Center), Shenzhen, 518035, PR China; Clinical Medicine College of Anhui Medical University, Department of Orthopedics, Shenzhen Second People′s Hospital, Shenzhen, 518000, Guangdong, PR ChinaShenzhen Key Laboratory of Tissue Engineering, Shenzhen Laboratory of Digital Orthopedic Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University, Health Science Center), Shenzhen, 518035, PR China; Clinical Medicine College of Anhui Medical University, Department of Orthopedics, Shenzhen Second People′s Hospital, Shenzhen, 518000, Guangdong, PR ChinaShenzhen Key Laboratory of Tissue Engineering, Shenzhen Laboratory of Digital Orthopedic Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University, Health Science Center), Shenzhen, 518035, PR China; Guangdong Provincial Research Center for Artificial Intelligence and Digital Orthopedic Technology, Shenzhen, 518035, PR China; Corresponding author. Shenzhen Key Laboratory of Tissue Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University), Shenzhen, 518035, Guangdong Province, PR China.Shenzhen Key Laboratory of Tissue Engineering, Shenzhen Laboratory of Digital Orthopedic Engineering, Shenzhen Second People's Hospital (The First Hospital Affiliated to Shenzhen University, Health Science Center), Shenzhen, 518035, PR China; Guangdong Provincial Research Center for Artificial Intelligence and Digital Orthopedic Technology, Shenzhen, 518035, PR China; Corresponding author. Shenzhen second People's Hospital, Shenzhen Training Base, Bone arthroscopy, Ministry of Health. Guangdong province, Shenzhen, 518035, PR China.Background: Chondromyxoid fibroma (CMF) is a very rare case usually appears around the knee. CMF presented high recurrence rate 25% among treated cases. However, in this case, interestingly CMF in the right upper arm was radiologically and pathologically diagnosed. It measures a 6.9 mm × 1.7 mm lesion. Case presentation: 36-year-old male showed CMF in the juxtacortic proximal humerus. Computed tomography (CT) and magnetic resonance imaging (MRI) of the right upper arm interestingly presented an expansile, mildly lobulated, septate lesion a 6.9 mm × 1.7 mm. Pathological analysis of biopsy showed a bony tissue consisting of cartilaginous, fibrous and myxoid stroma with abundant stellate shaped cells that present vary nucleus size and a minority of nuclear division. Surgical allogeneic bone graft and plate internal fixation was performed after the intralesional curettage surgery. Postoperation the patient was received doxorubicin 50–75 mg/m2 21 days cycle. Results showed that the intralesional curettage surgery of CMF, allogeneic bone graft and plate internal fixation combined with doxorubicin was successfully treated CMF and efficiently prevent relapse during 20 months of observations. Conclusion: the juxtacortic CMF was unusually diagnosed in the proximal humerus, it has been efficiently eliminated by a surgical operation and doxorubicin 50–75 mg/m2 that prevented tumor recurrence. Keywords: Chondromyxoid fibroma, Juxtacortic, Proximal humerus, Bone fibromahttp://www.sciencedirect.com/science/article/pii/S2214854X20300054 |
| spellingShingle | Murad Alahdal Yaoxi Li Gaorui Cai Li Duan Daping Wang A rare case of juxtacortic chondromyxoid fibroma in proximal humerus Translational Research in Anatomy |
| title | A rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| title_full | A rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| title_fullStr | A rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| title_full_unstemmed | A rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| title_short | A rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| title_sort | rare case of juxtacortic chondromyxoid fibroma in proximal humerus |
| url | http://www.sciencedirect.com/science/article/pii/S2214854X20300054 |
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