TIGIT as a Promising Therapeutic Target in Autoimmune Diseases

TIGIT as a Promising Therapeutic Target in Autoimmune Diseases

Co-inhibitory receptors (IRs) are molecules that protect host against autoimmune reactions and maintain peripheral self-tolerance, playing an essential role in maintaining immune homeostasis. In view of the substantial clinical progresses of negative immune checkpoint blockade in cancer treatment, t...

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Bibliographic Details
Main Authors: Chenran Yue, Sheng Gao, Shuting Li, Zhouhang Xing, Hengrong Qian, Ying Hu, Wenqian Wang, Chunyan Hua
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
autoimmunity
TIGIT
immune regulation
therapeutic target
co-inhibitory receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.911919/full

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