Association between electroencephalogram-based sleep characteristics and physical health in the general adult population
Abstract We examined the associations between electroencephalogram (EEG)-based sleep characteristics and physical health parameters in general adults via a cross-sectional study recruiting 100 volunteers aged 30–59 years. Sleep characteristics were measured at home using a portable multichannel elec...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-12-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-47979-9 |
| _version_ | 1827590590665064448 |
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| author | Masao Iwagami Jaehoon Seol Tetsuro Hiei Akihiro Tani Shigeru Chiba Takashi Kanbayashi Hideaki Kondo Takashi Tanaka Masashi Yanagisawa |
| author_facet | Masao Iwagami Jaehoon Seol Tetsuro Hiei Akihiro Tani Shigeru Chiba Takashi Kanbayashi Hideaki Kondo Takashi Tanaka Masashi Yanagisawa |
| author_sort | Masao Iwagami |
| collection | DOAJ |
| description | Abstract We examined the associations between electroencephalogram (EEG)-based sleep characteristics and physical health parameters in general adults via a cross-sectional study recruiting 100 volunteers aged 30–59 years. Sleep characteristics were measured at home using a portable multichannel electroencephalography recorder. Using the k-means + + clustering method, according to 10 EEG-based parameters, participants were grouped into better (n = 39), middle (n = 46), and worse (n = 15) sleep groups. Comparing 50 physical health parameters among the groups, we identified four signals of difference (P < 0.05), including systolic (sBP) and diastolic blood pressure (dBP), γ-glutamyl transpeptidase (γ-GTP), and serum creatinine, where sBP reached a Bonferroni-corrected threshold (P < 0.001). The sBP was higher by 7.9 (95% confidence interval 1.9–13.9) and 15.7 (7.3–24.0) mmHg before adjustment and 5.4 (− 0.1–10.9) and 8.7 (1.1–16.3) mmHg after adjustment for age, sex, body mass index, smoking, drinking habits, and 3% oxygen desaturation index in the middle and worse sleep groups, respectively, than in the better group. As another approach, among 500 combinations of EEG-based and physical health parameters, there were 45 signals of correlation, of which 4 (N1% and sBP, dBP, γ-GTP, and triglycerides) reached a Bonferroni-corrected threshold (P < 0.0001). Thus, EEG-based sleep characteristics are associated with several physical health parameters, particularly sBP. |
| first_indexed | 2024-03-09T01:18:58Z |
| format | Article |
| id | doaj.art-d10e69d834714b46844e3e86ea478c4f |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-09T01:18:58Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-d10e69d834714b46844e3e86ea478c4f2023-12-10T12:19:57ZengNature PortfolioScientific Reports2045-23222023-12-0113111110.1038/s41598-023-47979-9Association between electroencephalogram-based sleep characteristics and physical health in the general adult populationMasao Iwagami0Jaehoon Seol1Tetsuro Hiei2Akihiro Tani3Shigeru Chiba4Takashi Kanbayashi5Hideaki Kondo6Takashi Tanaka7Masashi Yanagisawa8International Institute for Integrative Sleep Medicine (IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (IIIS), University of TsukubaS’UIMIN Inc.S’UIMIN Inc.International Institute for Integrative Sleep Medicine (IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (IIIS), University of TsukubaInternational Institute for Integrative Sleep Medicine (IIIS), University of TsukubaKRD NihombashiInternational Institute for Integrative Sleep Medicine (IIIS), University of TsukubaAbstract We examined the associations between electroencephalogram (EEG)-based sleep characteristics and physical health parameters in general adults via a cross-sectional study recruiting 100 volunteers aged 30–59 years. Sleep characteristics were measured at home using a portable multichannel electroencephalography recorder. Using the k-means + + clustering method, according to 10 EEG-based parameters, participants were grouped into better (n = 39), middle (n = 46), and worse (n = 15) sleep groups. Comparing 50 physical health parameters among the groups, we identified four signals of difference (P < 0.05), including systolic (sBP) and diastolic blood pressure (dBP), γ-glutamyl transpeptidase (γ-GTP), and serum creatinine, where sBP reached a Bonferroni-corrected threshold (P < 0.001). The sBP was higher by 7.9 (95% confidence interval 1.9–13.9) and 15.7 (7.3–24.0) mmHg before adjustment and 5.4 (− 0.1–10.9) and 8.7 (1.1–16.3) mmHg after adjustment for age, sex, body mass index, smoking, drinking habits, and 3% oxygen desaturation index in the middle and worse sleep groups, respectively, than in the better group. As another approach, among 500 combinations of EEG-based and physical health parameters, there were 45 signals of correlation, of which 4 (N1% and sBP, dBP, γ-GTP, and triglycerides) reached a Bonferroni-corrected threshold (P < 0.0001). Thus, EEG-based sleep characteristics are associated with several physical health parameters, particularly sBP.https://doi.org/10.1038/s41598-023-47979-9 |
| spellingShingle | Masao Iwagami Jaehoon Seol Tetsuro Hiei Akihiro Tani Shigeru Chiba Takashi Kanbayashi Hideaki Kondo Takashi Tanaka Masashi Yanagisawa Association between electroencephalogram-based sleep characteristics and physical health in the general adult population Scientific Reports |
| title | Association between electroencephalogram-based sleep characteristics and physical health in the general adult population |
| title_full | Association between electroencephalogram-based sleep characteristics and physical health in the general adult population |
| title_fullStr | Association between electroencephalogram-based sleep characteristics and physical health in the general adult population |
| title_full_unstemmed | Association between electroencephalogram-based sleep characteristics and physical health in the general adult population |
| title_short | Association between electroencephalogram-based sleep characteristics and physical health in the general adult population |
| title_sort | association between electroencephalogram based sleep characteristics and physical health in the general adult population |
| url | https://doi.org/10.1038/s41598-023-47979-9 |
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