Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes

Transcriptome Analysis of Kidney Grafts Subjected to Normothermic Ex Vivo Perfusion Demonstrates an Enrichment of Mitochondrial Metabolism Genes

Background. Normothermic ex vivo kidney perfusion (NEVKP) has demonstrated superior outcomes for donation-after-cardiovascular death grafts compared with static cold storage (SCS). To determine the mechanisms responsible for this, we performed an unbiased genome-wide microarray analysis. Methods. Ki...

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Bibliographic Details
Main Authors: Peter Urbanellis, MD, PhD, Caitriona M. McEvoy, MD, PhD, Marko Škrtić, MD, PhD, J. Moritz Kaths, MD, Dagmar Kollmann, MD, PhD, Ivan Linares, MD, PhD, Sujani Ganesh, MSc, Fabiola Oquendo, MD, Manraj Sharma, BSc (Hons), Laura Mazilescu, MD, Toru Goto, MD, Yuki Noguchi, MD, PhD, Rohan John, MD, Istvan Mucsi, MD, PhD, Anand Ghanekar, MD, PhD, Darius Bagli, MD, Ana Konvalinka, MD, PhD, Markus Selzner, MD, Lisa A. Robinson, MD
Format: Article
Language:English
Published: Wolters Kluwer 2021-08-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001157

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