A Computational Method for the Binding Mode Prediction of COX-1 and COX-2 Inhibitors: Analyzing the Union of Coxibs, Oxicams, Propionic and Acetic Acids

A Computational Method for the Binding Mode Prediction of COX-1 and COX-2 Inhibitors: Analyzing the Union of Coxibs, Oxicams, Propionic and Acetic Acids

Among the biological targets extensively investigated to improve inflammation and chronic inflammatory conditions, cyclooxygenase enzymes (COXs) occupy a prominent position. The inhibition of these enzymes, essential for mitigating inflammatory processes, is chiefly achieved through Non-Steroidal An...

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Bibliographic Details
Main Authors: Estefany Bello-Vargas, Mario Alberto Leyva-Peralta, Zeferino Gómez-Sandoval, Mario Ordóñez, Rodrigo Said Razo-Hernández
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceuticals
Subjects:
anti-inflammatory
cyclooxygenase (COXs)
molecular docking
NSAIDs
Celecoxib
Meloxicam
Online Access:https://www.mdpi.com/1424-8247/16/12/1688

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