Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Protein deubiquitylase USP3 stabilizes Aurora A to promote proliferation and metastasis of esophageal squamous cell carcinoma

Abstract Aurora A kinase is a cell cycle regulator that is dysregulated in several different malignancies. Nevertheless, its regulatory mechanisms are still not fully understood. Here, we report that ubiquitin specific peptidase 3 (USP3) promotes proliferation and metastasis of esophageal squamous c...

Full description

Bibliographic Details
Main Authors: Ke Shi, Jin Zhong Zhang, Liang Yang, Ning-Ning Li, Ying Yue, Xiu-Hong Du, Xiu-Zhi Zhang, Yu Cheng Lu, Dan Guo
Format: Article
Language:English
Published: BMC 2021-11-01
Series:BMC Cancer
Subjects:
Aurora A
USP3
Ubiquitination
EMT
Esophageal squamous cell carcinoma
Online Access:https://doi.org/10.1186/s12885-021-08934-x

Similar Items

Similar Items