A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint
An osteolytic lesion on imaging can be considered malignancy until proven otherwise. However, advanced stages of gout have presented with sclerotic rims and lytic lesions thought to be due to overexpression of osteoclasts. Patients have been found to demonstrate osteolytic lesions in patellar region...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-11-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043322006975 |
| _version_ | 1828111597005963264 |
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| author | Sewar Abuarqob, MD Brooke Kania, DO Moutaz Ghrewati, MD Leena Bondili, MD Vinod Kumar, MD Michael Maroules, MD |
| author_facet | Sewar Abuarqob, MD Brooke Kania, DO Moutaz Ghrewati, MD Leena Bondili, MD Vinod Kumar, MD Michael Maroules, MD |
| author_sort | Sewar Abuarqob, MD |
| collection | DOAJ |
| description | An osteolytic lesion on imaging can be considered malignancy until proven otherwise. However, advanced stages of gout have presented with sclerotic rims and lytic lesions thought to be due to overexpression of osteoclasts. Patients have been found to demonstrate osteolytic lesions in patellar regions, which are common locations for gout to manifest; however, to our knowledge, no other cases of osteolytic gout in the acromioclavicular joint have been reported at this time. We report a rare case of a 56-year-old male who presented with acute-on-chronic left upper extremity pain and was found to have an osteolytic lesion of the shoulder on imaging. This lesion was later biopsied and found to be histologically consistent with gout. This case report aims to elucidate further understanding of the various ways that gout can present, to diagnose and treat these patients more effectively. |
| first_indexed | 2024-04-11T11:37:09Z |
| format | Article |
| id | doaj.art-d115e86afca541568488e34051efb5e9 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-04-11T11:37:09Z |
| publishDate | 2022-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-d115e86afca541568488e34051efb5e92022-12-22T04:25:55ZengElsevierRadiology Case Reports1930-04332022-11-01171143884391A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular jointSewar Abuarqob, MD0Brooke Kania, DO1Moutaz Ghrewati, MD2Leena Bondili, MD3Vinod Kumar, MD4Michael Maroules, MD5Departments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USACorresponding author.; Departments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USADepartments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USADepartments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USADepartments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USADepartments of Hematology/Oncology and Internal Medicine, St. Joseph's University Medical Center, 703 Main St, Paterson, NJ 07503, USAAn osteolytic lesion on imaging can be considered malignancy until proven otherwise. However, advanced stages of gout have presented with sclerotic rims and lytic lesions thought to be due to overexpression of osteoclasts. Patients have been found to demonstrate osteolytic lesions in patellar regions, which are common locations for gout to manifest; however, to our knowledge, no other cases of osteolytic gout in the acromioclavicular joint have been reported at this time. We report a rare case of a 56-year-old male who presented with acute-on-chronic left upper extremity pain and was found to have an osteolytic lesion of the shoulder on imaging. This lesion was later biopsied and found to be histologically consistent with gout. This case report aims to elucidate further understanding of the various ways that gout can present, to diagnose and treat these patients more effectively.http://www.sciencedirect.com/science/article/pii/S1930043322006975Tophaceous goutOsteolytic lesionGout flareChronic goutAcromioclavicular jointOsteoclast overexpression |
| spellingShingle | Sewar Abuarqob, MD Brooke Kania, DO Moutaz Ghrewati, MD Leena Bondili, MD Vinod Kumar, MD Michael Maroules, MD A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint Radiology Case Reports Tophaceous gout Osteolytic lesion Gout flare Chronic gout Acromioclavicular joint Osteoclast overexpression |
| title | A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| title_full | A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| title_fullStr | A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| title_full_unstemmed | A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| title_short | A rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| title_sort | rare case of tophaceous gout manifesting as an osteolytic lesion of the acromioclavicular joint |
| topic | Tophaceous gout Osteolytic lesion Gout flare Chronic gout Acromioclavicular joint Osteoclast overexpression |
| url | http://www.sciencedirect.com/science/article/pii/S1930043322006975 |
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