Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274

Inhibition of phosphorylated c-Met in rhabdomyosarcoma cell lines by a small molecule inhibitor SU11274

<p>Abstract</p> <p>Background</p> <p>c-Met is a receptor tyrosine kinase (RTK) that is over-expressed in a variety of cancers and involved in cell growth, invasion, metastasis and angiogenesis. In this study, we investigated the role of c-Met in rhabdomyosarcoma (RMS) u...

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Bibliographic Details
Main Authors: Li Yan, Zheng Jialin, Wang Jing, Geng Liying, Sun Lijun, Dong Jixin, Hou Jinxuan, Bridge Julia, Hinrichs Steven H, Ding Shi-Jian
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/9/1/64

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