Comparative study of the inhibitory effect on bone erosion progression with denosumab treatment and conventional treatment in rheumatoid arthritis patients: study protocol for an open-label randomized controlled trial by HR-pQCT
Abstract Background Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints, causes joint destruction, and leads to physical disability. Advances in the treatment of RA, such as biologic disease-modifying anti-rheumatic drugs (DMARDs), have provided better clinical outcomes, includ...
Main Authors: | Naoki Iwamoto, Shuntaro Sato, Remi Sumiyoshi, Ko Chiba, Nanami Miyamoto, Kumiko Arinaga, Makiko Kobayashi, Hiroshi Yamamoto, Makoto Osaki, Atsushi Kawakami |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | Trials |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13063-019-3589-8 |
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