Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice

Hesperetin promotes longevity and delays aging via activation of Cisd2 in naturally aged mice

Abstract Background The human CISD2 gene is located within a longevity region mapped on chromosome 4q. In mice, Cisd2 levels decrease during natural aging and genetic studies have shown that a high level of Cisd2 prolongs mouse lifespan and healthspan. Here, we evaluate the feasibility of using a Ci...

Full description

Bibliographic Details
Main Authors: Chi-Hsiao Yeh, Zhao-Qing Shen, Tai-Wen Wang, Cheng-Heng Kao, Yuan-Chi Teng, Teng-Kuang Yeh, Chung-Kuang Lu, Ting-Fen Tsai
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Biomedical Science
Subjects:
Longevity
Natural aging
Cisd2
Hesperetin
Online Access:https://doi.org/10.1186/s12929-022-00838-7

Similar Items

Similar Items