Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study

Abstract Background Dialectical behavioral therapy (DBT) skills have become increasingly used to treat several psychiatric conditions, including major depressive disorder (MDD). The aim of the study was to investigate the efficacy of an intervention that combines emotion regulation and mindfulness s...

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Main Authors: Matilde Elices, Joaquim Soler, Albert Feliu-Soler, Cristina Carmona, Thais Tiana, Juan C. Pascual, Azucena García-Palacios, Enric Álvarez
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Borderline Personality Disorder and Emotion Dysregulation
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40479-017-0064-6
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author Matilde Elices
Joaquim Soler
Albert Feliu-Soler
Cristina Carmona
Thais Tiana
Juan C. Pascual
Azucena García-Palacios
Enric Álvarez
author_facet Matilde Elices
Joaquim Soler
Albert Feliu-Soler
Cristina Carmona
Thais Tiana
Juan C. Pascual
Azucena García-Palacios
Enric Álvarez
author_sort Matilde Elices
collection DOAJ
description Abstract Background Dialectical behavioral therapy (DBT) skills have become increasingly used to treat several psychiatric conditions, including major depressive disorder (MDD). The aim of the study was to investigate the efficacy of an intervention that combines emotion regulation and mindfulness skills of DBT to prevent depression relapse/recurrence. Methods A total of 75 individuals (79% females; mean age, 52 years) with a diagnosis of MDD in complete or partial remission were recruited. Participants were randomly allocated either to an intervention combining emotion regulation and mindfulness skills (ER + M group, n = 37) or to a psychoeducative program (n = 38). After the 10-week treatment period, participants were followed for 1 year. Analyses were run in per-protocol (PP) and intention-to-treat (ITT) samples. The primary outcome measure was time to depression relapse/recurrence. Results ER + M training was not more effective than the control intervention in preventing depression relapse. However, PP and ITT analyses showed that participants trained in ER + M presented a significant reduction in depressive symptoms and overall psychopathology. Based on the PP and ITT analyses, neither of the interventions were related with an increase in dispositional mindfulness. Conclusions More studies are needed to confirm the efficacy of ER + M to decrease depressive symptoms and overall psychopathology. Trial registration NCT02747134 . Registered on 20 April 2016.
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spelling doaj.art-d11e49d56534464181603698bb70e6152022-12-21T19:37:58ZengBMCBorderline Personality Disorder and Emotion Dysregulation2051-66732017-07-01411910.1186/s40479-017-0064-6Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled studyMatilde Elices0Joaquim Soler1Albert Feliu-Soler2Cristina Carmona3Thais Tiana4Juan C. Pascual5Azucena García-Palacios6Enric Álvarez7Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Servei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Universitat Jaume IServei de Psiquiatria, Hospital de la Santa Creu i Sant Pau (Barcelona)Abstract Background Dialectical behavioral therapy (DBT) skills have become increasingly used to treat several psychiatric conditions, including major depressive disorder (MDD). The aim of the study was to investigate the efficacy of an intervention that combines emotion regulation and mindfulness skills of DBT to prevent depression relapse/recurrence. Methods A total of 75 individuals (79% females; mean age, 52 years) with a diagnosis of MDD in complete or partial remission were recruited. Participants were randomly allocated either to an intervention combining emotion regulation and mindfulness skills (ER + M group, n = 37) or to a psychoeducative program (n = 38). After the 10-week treatment period, participants were followed for 1 year. Analyses were run in per-protocol (PP) and intention-to-treat (ITT) samples. The primary outcome measure was time to depression relapse/recurrence. Results ER + M training was not more effective than the control intervention in preventing depression relapse. However, PP and ITT analyses showed that participants trained in ER + M presented a significant reduction in depressive symptoms and overall psychopathology. Based on the PP and ITT analyses, neither of the interventions were related with an increase in dispositional mindfulness. Conclusions More studies are needed to confirm the efficacy of ER + M to decrease depressive symptoms and overall psychopathology. Trial registration NCT02747134 . Registered on 20 April 2016.http://link.springer.com/article/10.1186/s40479-017-0064-6MindfulnessEmotion regulationMajor depressionRelapseRecurrence
spellingShingle Matilde Elices
Joaquim Soler
Albert Feliu-Soler
Cristina Carmona
Thais Tiana
Juan C. Pascual
Azucena García-Palacios
Enric Álvarez
Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
Borderline Personality Disorder and Emotion Dysregulation
Mindfulness
Emotion regulation
Major depression
Relapse
Recurrence
title Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
title_full Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
title_fullStr Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
title_full_unstemmed Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
title_short Combining emotion regulation and mindfulness skills for preventing depression relapse: a randomized-controlled study
title_sort combining emotion regulation and mindfulness skills for preventing depression relapse a randomized controlled study
topic Mindfulness
Emotion regulation
Major depression
Relapse
Recurrence
url http://link.springer.com/article/10.1186/s40479-017-0064-6
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