QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION
Aim. To investigate on the QRS complex fragmentation (fQRS) in patients with idiopathic ventricular arrhythmias (VA) .Material and methods. Totally, 125 patients, selected into 2 groups: 1st group — 100 patients (mean age 46,4±14,1 y., 69 females) with idiopathic VRD. Patients had predominating dayt...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2017-10-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/937 |
| _version_ | 1826561271451877376 |
|---|---|
| author | E. V. Parmon M. S. Gordeeva T. A. Kurilenko T E. R. Berngardt |
| author_facet | E. V. Parmon M. S. Gordeeva T. A. Kurilenko T E. R. Berngardt |
| author_sort | E. V. Parmon |
| collection | DOAJ |
| description | Aim. To investigate on the QRS complex fragmentation (fQRS) in patients with idiopathic ventricular arrhythmias (VA) .Material and methods. Totally, 125 patients, selected into 2 groups: 1st group — 100 patients (mean age 46,4±14,1 y., 69 females) with idiopathic VRD. Patients had predominating daytime arrhythmia (63%), more oftenly — monomorphic ventricular exstrasystolic complexes (VE) (59%), in 39% patients — paroxysms of nonsustained ventricular tachicardia. Structural pathology of myocardium was ruled out based on electrocardiography data, echocardiography, in some cases — magnetic resonance. Second, control group — 25 pts. (69,0±11 y. o., 12 females) with VRD of ischemic origin (coronary heart disease, myocardial infarction in anamnesis). In this group, polymorphic (84%) daytime (68%) VE predominated, and in 25% — nonsustained ventricular tachicardia. Analysis was done with Holter ECG in 12 leads (“KTResult 2”, “Inkart” JSC).Results. In the 1st group, fQRS of sinus complexes was registered in 2 patients (2%) and was transient. Relations in 24-hour dynamics of fQRS were not found. FQRS in VE was registered in 25 patients (25%). One patient had fQRS of sinus complexes as well as fQRS in VE. In 17 patients (68%) fQRS was found in VE. In controls, fQRS of sinus complexes was found in 6 patients (24%), fQRS of VE — in 23 (92%) and was permanent.Conclusion. The phenomenon of fQRS can be found during routine instrumental investigation (standard ECG or Holter ECG), and is more common for CHD patients, being significant criteria for repolarization processes evaluation. Looking for fQRS in patients with idiopathic VRD, probably, is related to dysbalance of autonomous nervous regulation that leads to electrical instability of myocardium. It cannot be ruled out that fQRS might be an early marker of cardiomyopathies. It is necessary to investigate on this phenomenon further and to find its place in risk stratification of sudden cardiac death of patients with no structural heart pathology. |
| first_indexed | 2024-04-09T20:48:14Z |
| format | Article |
| id | doaj.art-d11fb8559ce1478da1940a94d55720ce |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:29:31Z |
| publishDate | 2017-10-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-d11fb8559ce1478da1940a94d55720ce2025-03-02T11:42:42Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202017-10-0108909510.15829/1560-4071-2017-8-90-951643QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATIONE. V. Parmon0M. S. Gordeeva1T. A. Kurilenko T2E. R. Berngardt3Federal Almazov North-West Medical Research Centre of the Ministry of HealthFederal Almazov North-West Medical Research Centre of the Ministry of HealthFederal Almazov North-West Medical Research Centre of the Ministry of HealthFederal Almazov North-West Medical Research Centre of the Ministry of HealthAim. To investigate on the QRS complex fragmentation (fQRS) in patients with idiopathic ventricular arrhythmias (VA) .Material and methods. Totally, 125 patients, selected into 2 groups: 1st group — 100 patients (mean age 46,4±14,1 y., 69 females) with idiopathic VRD. Patients had predominating daytime arrhythmia (63%), more oftenly — monomorphic ventricular exstrasystolic complexes (VE) (59%), in 39% patients — paroxysms of nonsustained ventricular tachicardia. Structural pathology of myocardium was ruled out based on electrocardiography data, echocardiography, in some cases — magnetic resonance. Second, control group — 25 pts. (69,0±11 y. o., 12 females) with VRD of ischemic origin (coronary heart disease, myocardial infarction in anamnesis). In this group, polymorphic (84%) daytime (68%) VE predominated, and in 25% — nonsustained ventricular tachicardia. Analysis was done with Holter ECG in 12 leads (“KTResult 2”, “Inkart” JSC).Results. In the 1st group, fQRS of sinus complexes was registered in 2 patients (2%) and was transient. Relations in 24-hour dynamics of fQRS were not found. FQRS in VE was registered in 25 patients (25%). One patient had fQRS of sinus complexes as well as fQRS in VE. In 17 patients (68%) fQRS was found in VE. In controls, fQRS of sinus complexes was found in 6 patients (24%), fQRS of VE — in 23 (92%) and was permanent.Conclusion. The phenomenon of fQRS can be found during routine instrumental investigation (standard ECG or Holter ECG), and is more common for CHD patients, being significant criteria for repolarization processes evaluation. Looking for fQRS in patients with idiopathic VRD, probably, is related to dysbalance of autonomous nervous regulation that leads to electrical instability of myocardium. It cannot be ruled out that fQRS might be an early marker of cardiomyopathies. It is necessary to investigate on this phenomenon further and to find its place in risk stratification of sudden cardiac death of patients with no structural heart pathology.https://russjcardiol.elpub.ru/jour/article/view/937qrs fragmentationelectrical instability of myocardiumdepolarizationecgholter monitoringventricular arrhythmias (va). |
| spellingShingle | E. V. Parmon M. S. Gordeeva T. A. Kurilenko T E. R. Berngardt QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION Российский кардиологический журнал qrs fragmentation electrical instability of myocardium depolarization ecg holter monitoring ventricular arrhythmias (va). |
| title | QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION |
| title_full | QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION |
| title_fullStr | QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION |
| title_full_unstemmed | QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION |
| title_short | QRS COMPLEX FRAGMENTATION — AN IMPORTANT MARKER OF ABNORMAL DEPOLARIZATION |
| title_sort | qrs complex fragmentation an important marker of abnormal depolarization |
| topic | qrs fragmentation electrical instability of myocardium depolarization ecg holter monitoring ventricular arrhythmias (va). |
| url | https://russjcardiol.elpub.ru/jour/article/view/937 |
| work_keys_str_mv | AT evparmon qrscomplexfragmentationanimportantmarkerofabnormaldepolarization AT msgordeeva qrscomplexfragmentationanimportantmarkerofabnormaldepolarization AT takurilenkot qrscomplexfragmentationanimportantmarkerofabnormaldepolarization AT erberngardt qrscomplexfragmentationanimportantmarkerofabnormaldepolarization |