Mitochondrial DNA 4977 bp Deletion in Peripheral Blood Is Associated With Polycystic Ovary Syndrome

Mitochondrial DNA 4977 bp Deletion in Peripheral Blood Is Associated With Polycystic Ovary Syndrome

BackgroundPolycystic ovary syndrome (PCOS) is a common endocrine disorder worldwide. We aimed to examine the associations of two mitochondrial DNA (mtDNA) biomarkers in the peripheral blood, mtDNA copy number (CN), and mtDNA4977 deletion rate (DR), with PCOS in a clinical setting.MethodsWe performed...

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Bibliographic Details
Main Authors: Mujin Ye, Bin Hu, Weihui Shi, Fei Guo, Chenming Xu, Shuyuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
polycystic ovary syndrome
mitochondrial DNA deletion
mitochondrial DNA copy number
mitochondria
infertility
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.675581/full

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