Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape

Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape

Abstract Background Regulatory T cells (Tregs) induce immune responses and may contribute to immune escape in tumors. Accumulation of Tregs in tumors represents a critical barrier to anti-tumor immunity and immunotherapy. However, conflicting results describing the role of Tregs in lymphoma warrant...

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Bibliographic Details
Main Authors:	Xiuhua Su, Tao Sun, Meng Li, Yuan Xia, Mingying Li, Dongmei Wang, Fei Lu, Jingjing Ye, Chunyan Ji
Format:	Article
Language:	English
Published:	BMC 2022-08-01
Series:	Journal of Translational Medicine
Subjects:	Diffuse large B-cell lymphoma Regulatory T cells Lkb1 Immunosuppression Tumor immune microenvironment
Online Access:	https://doi.org/10.1186/s12967-022-03588-0

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