Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature
Abstract Background Gastric cancer rarely metastasizes to the gallbladder. Furthermore, there has never been a case report of simultaneous gallbladder metastasis from residual gastric cancer. Here, we report a case of synchronous gallbladder metastasis originating from a residual gastric cancer. Cas...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-05-01
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| Series: | Surgical Case Reports |
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| Online Access: | https://doi.org/10.1186/s40792-022-01442-5 |
| _version_ | 1818251070312284160 |
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| author | Ami Kawamoto Koichi Kimura Kosuke Hirose Takuma Izumi Daisuke Taniguchi Hiroko Yano Yuichiro Kajiwara Ryosuke Minagawa Kazuhito Minami Yumi Oshiro Takashi Nishizaki |
| author_facet | Ami Kawamoto Koichi Kimura Kosuke Hirose Takuma Izumi Daisuke Taniguchi Hiroko Yano Yuichiro Kajiwara Ryosuke Minagawa Kazuhito Minami Yumi Oshiro Takashi Nishizaki |
| author_sort | Ami Kawamoto |
| collection | DOAJ |
| description | Abstract Background Gastric cancer rarely metastasizes to the gallbladder. Furthermore, there has never been a case report of simultaneous gallbladder metastasis from residual gastric cancer. Here, we report a case of synchronous gallbladder metastasis originating from a residual gastric cancer. Case presentation A 67-year-old man underwent a follow-up upper endoscopy 18 months after a partial gastrectomy for gastric cancer; an ulcerative lesion was found in the remnant stomach at the gastrojejunal anastomosis. A biopsy revealed gastric signet-ring cell carcinoma (SRCC). A full-body examination revealed no abnormalities other than gallstones in the gallbladder. With a diagnosis of residual gastric cancer (cT2N0M0 cStage I), the patient underwent open total gastrectomy and cholecystectomy. Macroscopic findings of the resected specimen revealed thickening of the gallbladder wall; however, no obvious neoplastic lesions were found on the mucosal surface of the gallbladder. The pathological findings showed that the SRCC had invaded the submucosa of the gastrojejunostomy site with a high degree of lymphatic invasion and lymph node metastases. SRCCs were also found in the lymphatic vessels of the gallbladder wall. These findings suggested the possibility of gallbladder metastasis through lymphatic vessels. The patient and his family members refused postoperative chemotherapy. Ten months after the operation, the patient experienced respiratory failure due to lymphangitis carcinomatosa and died. Conclusions At present, it is difficult to determine whether resection of the gallbladder contributes to an improved prognosis of gastric cancer patients. However, reports in such cases demonstrate that gallbladder metastasis could be a poor predictor of prognosis for gastric cancer. |
| first_indexed | 2024-12-12T16:02:26Z |
| format | Article |
| id | doaj.art-d125a13b057b4053a8cde39313fc77b5 |
| institution | Directory Open Access Journal |
| issn | 2198-7793 |
| language | English |
| last_indexed | 2024-12-12T16:02:26Z |
| publishDate | 2022-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Surgical Case Reports |
| spelling | doaj.art-d125a13b057b4053a8cde39313fc77b52022-12-22T00:19:23ZengSpringerOpenSurgical Case Reports2198-77932022-05-01811710.1186/s40792-022-01442-5Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literatureAmi Kawamoto0Koichi Kimura1Kosuke Hirose2Takuma Izumi3Daisuke Taniguchi4Hiroko Yano5Yuichiro Kajiwara6Ryosuke Minagawa7Kazuhito Minami8Yumi Oshiro9Takashi Nishizaki10Department of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalDepartment of Pathology, Matsuyama Red Cross HospitalDepartment of Surgery, Matsuyama Red Cross HospitalAbstract Background Gastric cancer rarely metastasizes to the gallbladder. Furthermore, there has never been a case report of simultaneous gallbladder metastasis from residual gastric cancer. Here, we report a case of synchronous gallbladder metastasis originating from a residual gastric cancer. Case presentation A 67-year-old man underwent a follow-up upper endoscopy 18 months after a partial gastrectomy for gastric cancer; an ulcerative lesion was found in the remnant stomach at the gastrojejunal anastomosis. A biopsy revealed gastric signet-ring cell carcinoma (SRCC). A full-body examination revealed no abnormalities other than gallstones in the gallbladder. With a diagnosis of residual gastric cancer (cT2N0M0 cStage I), the patient underwent open total gastrectomy and cholecystectomy. Macroscopic findings of the resected specimen revealed thickening of the gallbladder wall; however, no obvious neoplastic lesions were found on the mucosal surface of the gallbladder. The pathological findings showed that the SRCC had invaded the submucosa of the gastrojejunostomy site with a high degree of lymphatic invasion and lymph node metastases. SRCCs were also found in the lymphatic vessels of the gallbladder wall. These findings suggested the possibility of gallbladder metastasis through lymphatic vessels. The patient and his family members refused postoperative chemotherapy. Ten months after the operation, the patient experienced respiratory failure due to lymphangitis carcinomatosa and died. Conclusions At present, it is difficult to determine whether resection of the gallbladder contributes to an improved prognosis of gastric cancer patients. However, reports in such cases demonstrate that gallbladder metastasis could be a poor predictor of prognosis for gastric cancer.https://doi.org/10.1186/s40792-022-01442-5Residual gastric cancerMetastasisSignet-ring cell carcinomaGallbladder |
| spellingShingle | Ami Kawamoto Koichi Kimura Kosuke Hirose Takuma Izumi Daisuke Taniguchi Hiroko Yano Yuichiro Kajiwara Ryosuke Minagawa Kazuhito Minami Yumi Oshiro Takashi Nishizaki Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature Surgical Case Reports Residual gastric cancer Metastasis Signet-ring cell carcinoma Gallbladder |
| title | Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature |
| title_full | Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature |
| title_fullStr | Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature |
| title_full_unstemmed | Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature |
| title_short | Synchronous gallbladder metastasis originating from residual gastric cancer: a case report and the review of literature |
| title_sort | synchronous gallbladder metastasis originating from residual gastric cancer a case report and the review of literature |
| topic | Residual gastric cancer Metastasis Signet-ring cell carcinoma Gallbladder |
| url | https://doi.org/10.1186/s40792-022-01442-5 |
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