Applying Protein–Protein Interactions and Complex Networks to Identify Novel Genes in Retinitis Pigmentosa Pathogenesis

Applying Protein–Protein Interactions and Complex Networks to Identify Novel Genes in Retinitis Pigmentosa Pathogenesis

Retinitis Pigmentosa (RP) is a hereditary retinal disorder that causes the atrophy of photoreceptor rod cells. Since individual defective genes converge on the same disease, we hypothesized that all causal genes of RP belong in a complex network. To explore this hypothesis, we conducted a gene conne...

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Bibliographic Details
Main Authors:	Su-Bin Yoon, Yu-Chien (Calvin) Ma, Akaash Venkat, Chun-Yu (Audi) Liu, Jie J. Zheng
Format:	Article
Language:	English
Published:	MDPI AG 2022-04-01
Series:	International Journal of Molecular Sciences
Subjects:	Retinitis Pigmentosa retinal degeneration protein interaction network (PIN) protein–protein interaction (PPI) complex networks network medicine
Online Access:	https://www.mdpi.com/1422-0067/23/7/3962

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