Locally generated C3 regulates the clearance of Toxoplasma gondii by IFN-γ-primed macrophage through regulation of xenophagy

Locally generated C3 regulates the clearance of Toxoplasma gondii by IFN-γ-primed macrophage through regulation of xenophagy

Exogenous pathogen infection can induce autophagy in cells. Autophagy is essential for cell survival, development, and homeostasis. It not only regulates cell defense and stress, but also has a close relationship with innate and adaptive immunity. Complement is an important part of innate immunity,...

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Bibliographic Details
Main Authors: Bo Liu, Yan Yan, Xiaoreng Wang, Nannan Chen, Jue Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Microbiology
Subjects:
autophagy
xenophagy
macrophage
Toxoplasma
C3
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.944006/full

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