Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex?
Negative pressure pulmonary edema is an uncommon cause of postoperative hypoxemia. Following upper air- way obstruction, negative pressure pulmonary edema oc- curs due to the generation of negative intrathoracic pres- sure by forceful inhalation against an obstructed upper airway. This complication...
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| Format: | Article |
| Language: | English |
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Pediatric Anesthesia and Critical Care Journal
2020-01-01
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| Series: | Pediatric Anesthesia and Critical Care Journal (PACCJ) |
| Subjects: | |
| Online Access: | http://www.anestesiarianimazione.com/PACCJ%202020/Negative%20pressure%20pulmonary%20edema%20causing%20postoperative%20hypoxemia%20is%20there%20a%20relationship%20with%20the%20administration%20of%20sugammadex.pdf |
| _version_ | 1827889426513002496 |
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| author | J.C. Stock G. Maves J. D. Tobias |
| author_facet | J.C. Stock G. Maves J. D. Tobias |
| author_sort | J.C. Stock |
| collection | DOAJ |
| description | Negative pressure pulmonary edema is an uncommon cause of postoperative hypoxemia. Following upper air- way obstruction, negative pressure pulmonary edema oc- curs due to the generation of negative intrathoracic pres- sure by forceful inhalation against an obstructed upper airway. This complication has previously been described in the context of laryngospasm during anesthetic care as well as a variety of other clinical scenarios including strangulation, foreign body aspiration, and obstructive sleep apnea. In the postoperative patient, management of this complication requires recognition and differentiation from other etiologies of hypoxemia. We present a 17- year-old adolescent who developed hypoxemia in the post-anesthesia care unit due to negative pressure pulmo- nary edema following laryngospasm during emergence from anesthesia and tracheal extubation. The differential diagnosis of postoperative hypoxemia in an otherwise healthy patient is presented, investigative work-up re- viewed, and treatment options discussed. Additionally, the anecdotal association of sugammadex with NPPE is outlined. |
| first_indexed | 2024-03-12T20:54:35Z |
| format | Article |
| id | doaj.art-d1281868b999403caea7680dd8853dc3 |
| institution | Directory Open Access Journal |
| issn | 2281-8421 |
| language | English |
| last_indexed | 2024-03-12T20:54:35Z |
| publishDate | 2020-01-01 |
| publisher | Pediatric Anesthesia and Critical Care Journal |
| record_format | Article |
| series | Pediatric Anesthesia and Critical Care Journal (PACCJ) |
| spelling | doaj.art-d1281868b999403caea7680dd8853dc32023-07-31T20:04:43ZengPediatric Anesthesia and Critical Care JournalPediatric Anesthesia and Critical Care Journal (PACCJ)2281-84212020-01-0182889310.14587/paccj.2020.14Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex?J.C. Stock0G. Maves1J. D. Tobias2Ohio University Heritage College of Osteopathic Medicine, Athens, Ohio, USADepartment of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, Ohio, USADepartment of Anesthesiology & Pain Medicine, The Ohio State University College of Medicine, Columbus, Ohio, USANegative pressure pulmonary edema is an uncommon cause of postoperative hypoxemia. Following upper air- way obstruction, negative pressure pulmonary edema oc- curs due to the generation of negative intrathoracic pres- sure by forceful inhalation against an obstructed upper airway. This complication has previously been described in the context of laryngospasm during anesthetic care as well as a variety of other clinical scenarios including strangulation, foreign body aspiration, and obstructive sleep apnea. In the postoperative patient, management of this complication requires recognition and differentiation from other etiologies of hypoxemia. We present a 17- year-old adolescent who developed hypoxemia in the post-anesthesia care unit due to negative pressure pulmo- nary edema following laryngospasm during emergence from anesthesia and tracheal extubation. The differential diagnosis of postoperative hypoxemia in an otherwise healthy patient is presented, investigative work-up re- viewed, and treatment options discussed. Additionally, the anecdotal association of sugammadex with NPPE is outlined.http://www.anestesiarianimazione.com/PACCJ%202020/Negative%20pressure%20pulmonary%20edema%20causing%20postoperative%20hypoxemia%20is%20there%20a%20relationship%20with%20the%20administration%20of%20sugammadex.pdfnegative pressure pulmonary edema; non-cardiogenic pulmonary edema; hypoxemia; laryngospasm; sugam- madex |
| spellingShingle | J.C. Stock G. Maves J. D. Tobias Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? Pediatric Anesthesia and Critical Care Journal (PACCJ) negative pressure pulmonary edema; non-cardiogenic pulmonary edema; hypoxemia; laryngospasm; sugam- madex |
| title | Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? |
| title_full | Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? |
| title_fullStr | Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? |
| title_full_unstemmed | Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? |
| title_short | Negative pressure pulmonary edema causing postoperative hypoxemia: is there a relationship with the administration of sugammadex? |
| title_sort | negative pressure pulmonary edema causing postoperative hypoxemia is there a relationship with the administration of sugammadex |
| topic | negative pressure pulmonary edema; non-cardiogenic pulmonary edema; hypoxemia; laryngospasm; sugam- madex |
| url | http://www.anestesiarianimazione.com/PACCJ%202020/Negative%20pressure%20pulmonary%20edema%20causing%20postoperative%20hypoxemia%20is%20there%20a%20relationship%20with%20the%20administration%20of%20sugammadex.pdf |
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