Clostridium difficile infection in a patient with Crohn disease
Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown. The authors report on a 14-year-old girl with Crohn disease who has acute gastrointestinal symptoms caus...
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| Format: | Article |
| Language: | English |
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Elsevier
2012-06-01
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| Series: | Journal of the Formosan Medical Association |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0929664612002471 |
| _version_ | 1811338668664684544 |
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| author | Chien-Hui Hsu Yung-Ming Jeng Yen-Hsuan Ni |
| author_facet | Chien-Hui Hsu Yung-Ming Jeng Yen-Hsuan Ni |
| author_sort | Chien-Hui Hsu |
| collection | DOAJ |
| description | Crohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown. The authors report on a 14-year-old girl with Crohn disease who has acute gastrointestinal symptoms caused by toxin A-producing Clostridium difficile, which mimicked a flare-up of Crohn disease. There was no preceding antibiotic prescription before the episode. The disease activity did not improve after steroid treatment, which is unusual for Crohn disease. However, all symptoms were dramatically relieved after eradication of C difficile, and led to a symptom-free period for more than 3 years. This case report aims to address the unusual presentation of a usual pathogen, C difficile, in a pediatric patient with Crohn disease. |
| first_indexed | 2024-04-13T18:15:33Z |
| format | Article |
| id | doaj.art-d1287d7cc47344fa843625ad2c56a46a |
| institution | Directory Open Access Journal |
| issn | 0929-6646 |
| language | English |
| last_indexed | 2024-04-13T18:15:33Z |
| publishDate | 2012-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of the Formosan Medical Association |
| spelling | doaj.art-d1287d7cc47344fa843625ad2c56a46a2022-12-22T02:35:43ZengElsevierJournal of the Formosan Medical Association0929-66462012-06-01111634734910.1016/j.jfma.2009.09.001Clostridium difficile infection in a patient with Crohn diseaseChien-Hui Hsu0Yung-Ming Jeng1Yen-Hsuan Ni2Department of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pathology, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanCrohn disease is a chronic inflammatory disorder, which is rare in pediatric patients. The definite etiology and mechanism to induce an acute exacerbation of Crohn disease remains mostly unknown. The authors report on a 14-year-old girl with Crohn disease who has acute gastrointestinal symptoms caused by toxin A-producing Clostridium difficile, which mimicked a flare-up of Crohn disease. There was no preceding antibiotic prescription before the episode. The disease activity did not improve after steroid treatment, which is unusual for Crohn disease. However, all symptoms were dramatically relieved after eradication of C difficile, and led to a symptom-free period for more than 3 years. This case report aims to address the unusual presentation of a usual pathogen, C difficile, in a pediatric patient with Crohn disease.http://www.sciencedirect.com/science/article/pii/S0929664612002471childrenClostridium difficileCrohn diseaseinflammatory bowel disease |
| spellingShingle | Chien-Hui Hsu Yung-Ming Jeng Yen-Hsuan Ni Clostridium difficile infection in a patient with Crohn disease Journal of the Formosan Medical Association children Clostridium difficile Crohn disease inflammatory bowel disease |
| title | Clostridium difficile infection in a patient with Crohn disease |
| title_full | Clostridium difficile infection in a patient with Crohn disease |
| title_fullStr | Clostridium difficile infection in a patient with Crohn disease |
| title_full_unstemmed | Clostridium difficile infection in a patient with Crohn disease |
| title_short | Clostridium difficile infection in a patient with Crohn disease |
| title_sort | clostridium difficile infection in a patient with crohn disease |
| topic | children Clostridium difficile Crohn disease inflammatory bowel disease |
| url | http://www.sciencedirect.com/science/article/pii/S0929664612002471 |
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