Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1

Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1

Autoimmune polyendocrine syndrome type 1 (APS1) is a rare monogenic autoimmune disorder caused by mutations in the autoimmune regulator (AIRE) gene. High titer autoantibodies are a characteristic feature of APS1 and are often associated with particular disease manifestations. Pituitary deficits are...

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Bibliographic Details
Main Authors: Casey J. A. Smith-Anttila, Sophie Bensing, Mohammad Alimohammadi, Frida Dalin, Mikael Oscarson, Ming-Dong Zhang, Jaakko Perheentupa, Eystein S. Husebye, Jan Gustafsson, Peyman Björklund, Anette Fransson, Gunnel Nordmark, Lars Rönnblom, Antonella Meloni, Rodney J. Scott, Tomas Hökfelt, Patricia A. Crock, Olle Kämpe
Format: Article
Language:English
Published: Taylor & Francis Group 2017-05-01
Series:Autoimmunity
Subjects:
aps1
endothelin-converting enzyme-2
ece-2
pituitary autoantibodies
pancreas
Online Access:http://dx.doi.org/10.1080/08916934.2017.1332183

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