Gingival epithelial cell-derived microvesicles activate mineralization in gingival fibroblasts

Abstract Soft tissue calcification occurs in many parts of the body, including the gingival tissue. Epithelial cell-derived MVs can control many functions in fibroblasts but their role in regulating mineralization has not been explored. We hypothesized that microvesicles (MVs) derived from gingival...

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Bibliographic Details
Main Authors: Shuichiro Kobayashi, Jiarui Bi, Gethin Owen, Nelli Larjava, Leeni Koivisto, Lari Häkkinen, Hannu Larjava
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-19732-1

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