National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019
Abstract Introduction Central nervous system cancers (CNS cancers) impose a significant burden upon healthcare systems worldwide. Currently, the lack of a comprehensive study to assess various epidemiological indexes of CNS cancers on national and subnational scales in Iran can hamper healthcare pla...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-04-01
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| Series: | Cancer Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/cam4.5553 |
| _version_ | 1827958750664720384 |
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| author | Mahdi Mahdavi Sahar Saeedi Moghaddam Mohsen Abbasi‐Kangevari Esmaeil Mohammadi Parnian Shobeiri Guive Sharifi Ali Jafari Negar Rezaei Narges Ebrahimi Nazila Rezaei Seyyed‐Hadi Ghamari Mohammad‐Reza Malekpour Majid Khalili Bagher Larijani Farzad Kompani |
| author_facet | Mahdi Mahdavi Sahar Saeedi Moghaddam Mohsen Abbasi‐Kangevari Esmaeil Mohammadi Parnian Shobeiri Guive Sharifi Ali Jafari Negar Rezaei Narges Ebrahimi Nazila Rezaei Seyyed‐Hadi Ghamari Mohammad‐Reza Malekpour Majid Khalili Bagher Larijani Farzad Kompani |
| author_sort | Mahdi Mahdavi |
| collection | DOAJ |
| description | Abstract Introduction Central nervous system cancers (CNS cancers) impose a significant burden upon healthcare systems worldwide. Currently, the lack of a comprehensive study to assess various epidemiological indexes of CNS cancers on national and subnational scales in Iran can hamper healthcare planning and resource allocation in this regard. This study aims to fill this gap by providing estimates of CNS cancer epidemiological measures on national and subnational levels in Iran from 1990 to 2019. Materials and Methods This study is a part of Global Burden of Disease (GBD) 2019 that contains epidemiological measures including prevalence, incidence, mortality, Disability‐Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) of CNS cancers. Age standardization was utilized for comparing different provinces. Results In 2019, 5811 (95% Uncertainty Interval: 2942–7046) national new cases and 3494 (1751–4173) deaths due to CNS cancers were reported. National age‐standardized incidence (ASIR), deaths (ASDR), and DALYs rates were 7.3 (3.7–8.8), 4.6 (2.3–5.5), and 156.4 (82.0–187.0) per 100,000 in 2019, respectively. Subnational results revealed that ASDR and ASIR have increased in the past 30 years in all provinces. Although incidence rates have increased in all age groups and genders since 1990, death rates have remained the same for most age groups and genders except for young patients aged under 15, where a decrease in mortality and YLLs can be observed. Conclusion The incidence, deaths, and DALYs of CNS cancers increased at national and subnational levels. These findings should be considered for planning and resource allocation. |
| first_indexed | 2024-04-09T15:41:16Z |
| format | Article |
| id | doaj.art-d13520a8952e47dba4549cdc8af18ba6 |
| institution | Directory Open Access Journal |
| issn | 2045-7634 |
| language | English |
| last_indexed | 2024-04-09T15:41:16Z |
| publishDate | 2023-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cancer Medicine |
| spelling | doaj.art-d13520a8952e47dba4549cdc8af18ba62023-04-27T10:12:44ZengWileyCancer Medicine2045-76342023-04-011278614862810.1002/cam4.5553National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019Mahdi Mahdavi0Sahar Saeedi Moghaddam1Mohsen Abbasi‐Kangevari2Esmaeil Mohammadi3Parnian Shobeiri4Guive Sharifi5Ali Jafari6Negar Rezaei7Narges Ebrahimi8Nazila Rezaei9Seyyed‐Hadi Ghamari10Mohammad‐Reza Malekpour11Majid Khalili12Bagher Larijani13Farzad Kompani14Non‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranDepartment of Neurosurgery, Loghman Hospital Shahid Beheshti University of Medical Sciences Tehran IranDepartment of Neurosurgery, Loghman Hospital Shahid Beheshti University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranNon‐Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute Tehran University of Medical Sciences Tehran IranEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran IranDivision of Hematology and Oncology, Children's Medical Center, Pediatrics Center of Excellence Tehran University of Medical Sciences Tehran IranAbstract Introduction Central nervous system cancers (CNS cancers) impose a significant burden upon healthcare systems worldwide. Currently, the lack of a comprehensive study to assess various epidemiological indexes of CNS cancers on national and subnational scales in Iran can hamper healthcare planning and resource allocation in this regard. This study aims to fill this gap by providing estimates of CNS cancer epidemiological measures on national and subnational levels in Iran from 1990 to 2019. Materials and Methods This study is a part of Global Burden of Disease (GBD) 2019 that contains epidemiological measures including prevalence, incidence, mortality, Disability‐Adjusted Life Years (DALYs), Years Lived with Disability (YLDs), and Years of Life Lost (YLLs) of CNS cancers. Age standardization was utilized for comparing different provinces. Results In 2019, 5811 (95% Uncertainty Interval: 2942–7046) national new cases and 3494 (1751–4173) deaths due to CNS cancers were reported. National age‐standardized incidence (ASIR), deaths (ASDR), and DALYs rates were 7.3 (3.7–8.8), 4.6 (2.3–5.5), and 156.4 (82.0–187.0) per 100,000 in 2019, respectively. Subnational results revealed that ASDR and ASIR have increased in the past 30 years in all provinces. Although incidence rates have increased in all age groups and genders since 1990, death rates have remained the same for most age groups and genders except for young patients aged under 15, where a decrease in mortality and YLLs can be observed. Conclusion The incidence, deaths, and DALYs of CNS cancers increased at national and subnational levels. These findings should be considered for planning and resource allocation.https://doi.org/10.1002/cam4.5553brain and central nervous system cancersepidemiologic studyglobal burden of diseaseIran |
| spellingShingle | Mahdi Mahdavi Sahar Saeedi Moghaddam Mohsen Abbasi‐Kangevari Esmaeil Mohammadi Parnian Shobeiri Guive Sharifi Ali Jafari Negar Rezaei Narges Ebrahimi Nazila Rezaei Seyyed‐Hadi Ghamari Mohammad‐Reza Malekpour Majid Khalili Bagher Larijani Farzad Kompani National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 Cancer Medicine brain and central nervous system cancers epidemiologic study global burden of disease Iran |
| title | National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 |
| title_full | National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 |
| title_fullStr | National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 |
| title_full_unstemmed | National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 |
| title_short | National and subnational burden of brain and central nervous system cancers in Iran, 1990–2019: Results from the global burden of disease study 2019 |
| title_sort | national and subnational burden of brain and central nervous system cancers in iran 1990 2019 results from the global burden of disease study 2019 |
| topic | brain and central nervous system cancers epidemiologic study global burden of disease Iran |
| url | https://doi.org/10.1002/cam4.5553 |
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