Intra-Arterial, but Not Intrathecal, Baclofen and Codeine Attenuates Cough in the Cat

Centrally-acting antitussive drugs are thought to act solely in the brainstem. However, the role of the spinal cord in the mechanism of action of these drugs is unknown. The purpose of this study was to determine if antitussive drugs act in the spinal cord to reduce the magnitude of tracheobronchial...

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Bibliographic Details
Main Authors: Wendy L. Olsen, Melanie Rose, Frank J. Golder, Cheng Wang, Julie C. Hammond, Donald C. Bolser
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.640682/full