Infiltrative optic neuropathy: A neuro-oncological emergency

Acute lymphoblastic leukemia (ALL) is a disorder caused by the abnormal proliferation of immature lymphocytes. Of the varied ocular manifestations seen in ALL, infiltration of the optic nerve is a rare and serious complication that heralds a relapse of the disease. It requires a high index of suspic...

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Main Authors: Akruti Gunderia, Padmavathy Maharajan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:TNOA Journal of Ophthalmic Science and Research
Subjects:
Online Access:http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2022;volume=60;issue=1;spage=110;epage=113;aulast=Gunderia
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author Akruti Gunderia
Padmavathy Maharajan
author_facet Akruti Gunderia
Padmavathy Maharajan
author_sort Akruti Gunderia
collection DOAJ
description Acute lymphoblastic leukemia (ALL) is a disorder caused by the abnormal proliferation of immature lymphocytes. Of the varied ocular manifestations seen in ALL, infiltration of the optic nerve is a rare and serious complication that heralds a relapse of the disease. It requires a high index of suspicion for diagnosis. Urgent intervention may prove to be lifesaving. We describe a case of optic neuropathy in a 12-year-old boy with ALL and wish to emphasize the need to maintain a low threshold for diagnosing optic nerve infiltration in patients with a prior history of leukemia.
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spelling doaj.art-d1374ccdbe0249b19a7d1ff8158c95752022-12-21T21:59:25ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362022-01-0160111011310.4103/tjosr.tjosr_72_21Infiltrative optic neuropathy: A neuro-oncological emergencyAkruti GunderiaPadmavathy MaharajanAcute lymphoblastic leukemia (ALL) is a disorder caused by the abnormal proliferation of immature lymphocytes. Of the varied ocular manifestations seen in ALL, infiltration of the optic nerve is a rare and serious complication that heralds a relapse of the disease. It requires a high index of suspicion for diagnosis. Urgent intervention may prove to be lifesaving. We describe a case of optic neuropathy in a 12-year-old boy with ALL and wish to emphasize the need to maintain a low threshold for diagnosing optic nerve infiltration in patients with a prior history of leukemia.http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2022;volume=60;issue=1;spage=110;epage=113;aulast=Gunderiaacute lymphoblastic leukemiaoptic nerve infiltrationoptic neuropathy
spellingShingle Akruti Gunderia
Padmavathy Maharajan
Infiltrative optic neuropathy: A neuro-oncological emergency
TNOA Journal of Ophthalmic Science and Research
acute lymphoblastic leukemia
optic nerve infiltration
optic neuropathy
title Infiltrative optic neuropathy: A neuro-oncological emergency
title_full Infiltrative optic neuropathy: A neuro-oncological emergency
title_fullStr Infiltrative optic neuropathy: A neuro-oncological emergency
title_full_unstemmed Infiltrative optic neuropathy: A neuro-oncological emergency
title_short Infiltrative optic neuropathy: A neuro-oncological emergency
title_sort infiltrative optic neuropathy a neuro oncological emergency
topic acute lymphoblastic leukemia
optic nerve infiltration
optic neuropathy
url http://www.tnoajosr.com/article.asp?issn=2589-4528;year=2022;volume=60;issue=1;spage=110;epage=113;aulast=Gunderia
work_keys_str_mv AT akrutigunderia infiltrativeopticneuropathyaneurooncologicalemergency
AT padmavathymaharajan infiltrativeopticneuropathyaneurooncologicalemergency