Mitochondrial Respiration in <i>KRAS</i> and <i>BRAF</i> Mutated Colorectal Tumors and Polyps

Mitochondrial Respiration in <i>KRAS</i> and <i>BRAF</i> Mutated Colorectal Tumors and Polyps

This study aimed to characterize the ATP-synthesis by oxidative phosphorylation in colorectal cancer (CRC) and premalignant colon polyps in relation to molecular biomarkers KRAS and BRAF. This prospective study included 48 patients. Resected colorectal polyps and postoperative CRC tissue with adjace...

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Bibliographic Details
Main Authors: Egle Rebane-Klemm, Laura Truu, Leenu Reinsalu, Marju Puurand, Igor Shevchuk, Vladimir Chekulayev, Natalja Timohhina, Kersti Tepp, Jelena Bogovskaja, Vladimir Afanasjev, Külliki Suurmaa, Vahur Valvere, Tuuli Kaambre
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Cancers
Subjects:
energy metabolism
colorectal cancer
colorectal polyps
mitochondria
oxidative phosphorylation
<i>KRAS</i>
Online Access:https://www.mdpi.com/2072-6694/12/4/815

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