Differences in primary and secondary stroke prevention strategies for Chinese men and women
This study aimed to explore whether stroke prevention strategies differ for men and women. Data used were from China Kadoorie Biobank. According to the China-PAR Project model, a predicted 10-year stroke risk of ≥7% is defined as a high stroke risk. The effects of risk factor control and medication...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Preventive Medicine Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211335523001109 |
| _version_ | 1797827804835872768 |
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| author | Zenghua Xie Xu Guo Liyuan Han Xin Wang Qianqian Yan Chang Shu Zhenyi Fan Miaomiao Zhao |
| author_facet | Zenghua Xie Xu Guo Liyuan Han Xin Wang Qianqian Yan Chang Shu Zhenyi Fan Miaomiao Zhao |
| author_sort | Zenghua Xie |
| collection | DOAJ |
| description | This study aimed to explore whether stroke prevention strategies differ for men and women. Data used were from China Kadoorie Biobank. According to the China-PAR Project model, a predicted 10-year stroke risk of ≥7% is defined as a high stroke risk. The effects of risk factor control and medication use as primary and secondary stroke prevention strategies were assessed, respectively. Logistic regression models were used to assess the sex-specific differences in the primary and secondary stroke prevention practices. Of the 512,715 participants (59.0% women), 218,972 (57.4% women) had a high risk of stroke and 8884 (44.7% women) had an established stroke. Of high-risk participants, women were considerably less likely than men to receive antiplatelets (odds ratio [OR], 0.80; [95% confidence interval, CI, 0.72–0.89]), antihypertensives (0.46[0.44–0.48]), and antidiabetics (0.65[0.60–0.70]). Meanwhile, stroke women were significantly less likely to receive antiplatelets (0.75[0.65–0.85]) but more likely to receive antidiabetics (1.56 [1.34–1.82]) than their male counterparts. Besides, differences were found in risk factor control between women and men. Sex-specific differences in stroke prevention strategies are prevalent in China. Effective prevention requires the implementation of better overall nationwide strategies and special emphasis on women. |
| first_indexed | 2024-04-09T12:54:14Z |
| format | Article |
| id | doaj.art-d13cd0105d3e4c1f93ee30dda896af2a |
| institution | Directory Open Access Journal |
| issn | 2211-3355 |
| language | English |
| last_indexed | 2024-04-09T12:54:14Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Preventive Medicine Reports |
| spelling | doaj.art-d13cd0105d3e4c1f93ee30dda896af2a2023-05-14T04:28:47ZengElsevierPreventive Medicine Reports2211-33552023-06-0133102219Differences in primary and secondary stroke prevention strategies for Chinese men and womenZenghua Xie0Xu Guo1Liyuan Han2Xin Wang3Qianqian Yan4Chang Shu5Zhenyi Fan6Miaomiao Zhao7Department of Neurology, Beilun District People’s Hospital, Ningbo, Zhejiang, ChinaDepartment of Rehabilitation Medicine, Hwa Mei Hospital, University of the Chinese Academy of Sciences, Ningbo, Zhejiang, ChinaHwa Mei Hospital, Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China; Department of Global Health, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, Zhejiang, ChinaDepartment of Neurology, Beilun District People’s Hospital, Ningbo, Zhejiang, ChinaHwa Mei Hospital, Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China; Department of Global Health, Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, Zhejiang, ChinaTianjin Cerebral Vascular and Neural Degenerative Disease Key Laboratory, Tianjin Neurosurgery Institute, Tianjin Huanhu Hospital, Tianjin, ChinaDepartment of Neurology, Hwa Mei Hospital, University of Chinese Academy of Science, Ningbo, Zhejiang, China; Corresponding authors.Department of Health Management, School of Public Health, Nantong University, Nantong, Jiangsu, China; Corresponding authors.This study aimed to explore whether stroke prevention strategies differ for men and women. Data used were from China Kadoorie Biobank. According to the China-PAR Project model, a predicted 10-year stroke risk of ≥7% is defined as a high stroke risk. The effects of risk factor control and medication use as primary and secondary stroke prevention strategies were assessed, respectively. Logistic regression models were used to assess the sex-specific differences in the primary and secondary stroke prevention practices. Of the 512,715 participants (59.0% women), 218,972 (57.4% women) had a high risk of stroke and 8884 (44.7% women) had an established stroke. Of high-risk participants, women were considerably less likely than men to receive antiplatelets (odds ratio [OR], 0.80; [95% confidence interval, CI, 0.72–0.89]), antihypertensives (0.46[0.44–0.48]), and antidiabetics (0.65[0.60–0.70]). Meanwhile, stroke women were significantly less likely to receive antiplatelets (0.75[0.65–0.85]) but more likely to receive antidiabetics (1.56 [1.34–1.82]) than their male counterparts. Besides, differences were found in risk factor control between women and men. Sex-specific differences in stroke prevention strategies are prevalent in China. Effective prevention requires the implementation of better overall nationwide strategies and special emphasis on women.http://www.sciencedirect.com/science/article/pii/S2211335523001109Stroke preventionMedication useRisk factor controlSex-specific differencesChina Kadoorie Biobank |
| spellingShingle | Zenghua Xie Xu Guo Liyuan Han Xin Wang Qianqian Yan Chang Shu Zhenyi Fan Miaomiao Zhao Differences in primary and secondary stroke prevention strategies for Chinese men and women Preventive Medicine Reports Stroke prevention Medication use Risk factor control Sex-specific differences China Kadoorie Biobank |
| title | Differences in primary and secondary stroke prevention strategies for Chinese men and women |
| title_full | Differences in primary and secondary stroke prevention strategies for Chinese men and women |
| title_fullStr | Differences in primary and secondary stroke prevention strategies for Chinese men and women |
| title_full_unstemmed | Differences in primary and secondary stroke prevention strategies for Chinese men and women |
| title_short | Differences in primary and secondary stroke prevention strategies for Chinese men and women |
| title_sort | differences in primary and secondary stroke prevention strategies for chinese men and women |
| topic | Stroke prevention Medication use Risk factor control Sex-specific differences China Kadoorie Biobank |
| url | http://www.sciencedirect.com/science/article/pii/S2211335523001109 |
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