Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease

Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease

Mitochondrial DNA regulates mitochondrial function which is altered in both idiopathic and familial forms of Parkinson's disease. To investigate whether these two disease forms exhibit an altered regulation of mitochondrial DNA we measured cell free mitochondrial DNA content in cerebrospinal fl...

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Bibliographic Details
Main Authors: Petar Podlesniy, Dolores Vilas, Peggy Taylor, Leslie M. Shaw, Eduard Tolosa, Ramon Trullas
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Neurobiology of Disease
Subjects:
Parkinson's disease
LRRK2
Mitochondrial DNA
Digital PCR
Online Access:http://www.sciencedirect.com/science/article/pii/S096999611630122X

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