Sex differences in pulmonary arterial hypertension: role of infection and autoimmunity in the pathogenesis of disease

Sex differences in pulmonary arterial hypertension: role of infection and autoimmunity in the pathogenesis of disease

Abstract Registry data worldwide indicate an overall female predominance for pulmonary arterial hypertension (PAH) of 2–4 over men. Genetic predisposition accounts for only 1–5% of PAH cases, while autoimmune diseases and infections are closely linked to PAH. Idiopathic PAH may include patients with...

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Bibliographic Details
Main Authors: Kyle A. Batton, Christopher O. Austin, Katelyn A. Bruno, Charles D. Burger, Brian P. Shapiro, DeLisa Fairweather
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Biology of Sex Differences
Subjects:
Pulmonary arterial hypertension
Sex differences
Autoimmune disease
Inflammation
Systemic sclerosis
Myocarditis
Online Access:http://link.springer.com/article/10.1186/s13293-018-0176-8

Internet

http://link.springer.com/article/10.1186/s13293-018-0176-8

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