Mandibular advancement devices in obstructive sleep apnea: an updated review

Obstructive sleep apnea (OSA) is the most prevalent sleep-disordered breathing in the adult population and if untreated remains a significant cause of morbidity and mortality. Continuous positive airway pressure (CPAP) therapy is still the gold standard treatment for OSA, but patient acceptance and...

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Main Authors: Izabella Paola Manetta, Dominik Ettlin, Pedro Mayoral Sanz, Isabel Rocha, Miguel Meira e Cruz
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda.
Series:Sleep Science
Subjects:
Online Access:https://cdn.publisher.gn1.link/sleepscience.org.br/pdf/v15nspe2a16.pdf
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author Izabella Paola Manetta
Dominik Ettlin
Pedro Mayoral Sanz
Isabel Rocha
Miguel Meira e Cruz
author_facet Izabella Paola Manetta
Dominik Ettlin
Pedro Mayoral Sanz
Isabel Rocha
Miguel Meira e Cruz
author_sort Izabella Paola Manetta
collection DOAJ
description Obstructive sleep apnea (OSA) is the most prevalent sleep-disordered breathing in the adult population and if untreated remains a significant cause of morbidity and mortality. Continuous positive airway pressure (CPAP) therapy is still the gold standard treatment for OSA, but patient acceptance and adherence are often poor due to a multitude of factors, thereby compromising treatment success. Mandibular advancement devices (MADs) have been proposed not only as a first line therapy for symptomatic snoring patients, but also for those suffering from mild to moderate OSA, or those who refuse or do not tolerate CPAP. Yet, improved understanding of MAD regarding design, construction, and mechanisms of action is an important requirement to successfully implement MAD as a therapeutic tool. Therefore, the main focus of this paper is to focus on the general concepts and mechanisms of action of MAD, while highlighting important characteristics in the context of their use as a viable and effective treatment option for OSA patients.
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spelling doaj.art-d14d98bd87564a5ab1c09670c87870be2024-02-03T01:15:06ZengThieme Revinter Publicações Ltda.Sleep Science1984-06591984-006315Special2398405001610.5935/1984-0063.20210032Mandibular advancement devices in obstructive sleep apnea: an updated reviewIzabella Paola Manetta0Dominik Ettlin1Pedro Mayoral Sanz2Isabel Rocha3Miguel Meira e Cruz4Department of Otolaryngology Pontificia, Universidade Católica de Campinas, - Campinas - São Paulo - Brazil.University of Zurich, Center of Dental Medicine - Zurich - Zurich - Switzerland.Catholic University of Murcia, Dental Sleep Medicine - Murcia - Murcia - Spain.Cardiovascular Autonomic Function Lab, Centro Cardiovascular da Universidade de Lisboa, Lisbon School of Medicine, Lisbon, Portugal.Sleep Unit, Centro Cardiovascular da Universidade de Lisboa, Lisbon School of Medicine, Lisbon, Portugal.Obstructive sleep apnea (OSA) is the most prevalent sleep-disordered breathing in the adult population and if untreated remains a significant cause of morbidity and mortality. Continuous positive airway pressure (CPAP) therapy is still the gold standard treatment for OSA, but patient acceptance and adherence are often poor due to a multitude of factors, thereby compromising treatment success. Mandibular advancement devices (MADs) have been proposed not only as a first line therapy for symptomatic snoring patients, but also for those suffering from mild to moderate OSA, or those who refuse or do not tolerate CPAP. Yet, improved understanding of MAD regarding design, construction, and mechanisms of action is an important requirement to successfully implement MAD as a therapeutic tool. Therefore, the main focus of this paper is to focus on the general concepts and mechanisms of action of MAD, while highlighting important characteristics in the context of their use as a viable and effective treatment option for OSA patients.https://cdn.publisher.gn1.link/sleepscience.org.br/pdf/v15nspe2a16.pdfsleep apneaobstructivemandibular advancementocclusal splints
spellingShingle Izabella Paola Manetta
Dominik Ettlin
Pedro Mayoral Sanz
Isabel Rocha
Miguel Meira e Cruz
Mandibular advancement devices in obstructive sleep apnea: an updated review
Sleep Science
sleep apnea
obstructive
mandibular advancement
occlusal splints
title Mandibular advancement devices in obstructive sleep apnea: an updated review
title_full Mandibular advancement devices in obstructive sleep apnea: an updated review
title_fullStr Mandibular advancement devices in obstructive sleep apnea: an updated review
title_full_unstemmed Mandibular advancement devices in obstructive sleep apnea: an updated review
title_short Mandibular advancement devices in obstructive sleep apnea: an updated review
title_sort mandibular advancement devices in obstructive sleep apnea an updated review
topic sleep apnea
obstructive
mandibular advancement
occlusal splints
url https://cdn.publisher.gn1.link/sleepscience.org.br/pdf/v15nspe2a16.pdf
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AT pedromayoralsanz mandibularadvancementdevicesinobstructivesleepapneaanupdatedreview
AT isabelrocha mandibularadvancementdevicesinobstructivesleepapneaanupdatedreview
AT miguelmeiraecruz mandibularadvancementdevicesinobstructivesleepapneaanupdatedreview