Mydriasis caused by ESCITALOPRAM: Case report
Introduction Serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants thanks to the overall safety and tolerability spectrum. However, they can cause different side effects that not all of them are well identified. Objectives We intend to clarify the clinical presenta...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822018788/type/journal_article |
| _version_ | 1797616467467829248 |
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| author | N. Bouattour W. Bouattour N. Messedi F. Charfeddine L. Aribi J. Aloulou |
| author_facet | N. Bouattour W. Bouattour N. Messedi F. Charfeddine L. Aribi J. Aloulou |
| author_sort | N. Bouattour |
| collection | DOAJ |
| description |
Introduction
Serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants thanks to the overall safety and tolerability spectrum. However, they can cause different side effects that not all of them are well identified.
Objectives
We intend to clarify the clinical presentation of mydriasis caused by Escitalopram.
Methods
Reporting the case of a patient suffering a major depressive disorder, that presented a mydriasis after adjusting her antidepressant medication. Then, we conducted a literature review using “PubMed” database and keywords “Mydriasis”, “escitalopram”, “SSRI”,” side effects”.
Results
A 29-year-old female with no past clinical history, presented in May 2021 a severe depression requiring an antidepressant treatment. Under 10 mg per day of escitalopram there was a partial remission of the symptoms, leading to increase the dose by another 10 mg. One month after taking 20 mg/day, she consults before the appointment suffering from a blurry vision and photophobia. Ophthalmologic examination showed a bilateral reactive half-mydriasis, eye pressure was 14 mmHg and fundus examination was normal. Iatrogenic origin of mydriasis was suspected. A gradual interruption of the medication lead to disappearance of the latter. A pharmacological investigation concluded to the suspension of escitalopram and to be vigilant if antidepressant medication would be needed.
Conclusions
Mydriasis is an uncommon side effect caused by SSRI that needs to be kept in mind by clinicians. Therapeutic patient education can help to detect abnormal side effects and treat them if needed.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:41:39Z |
| format | Article |
| id | doaj.art-d14e63d961b741ba87128746f1a877fd |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:41:39Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-d14e63d961b741ba87128746f1a877fd2023-11-17T05:08:28ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S727S72810.1192/j.eurpsy.2022.1878Mydriasis caused by ESCITALOPRAM: Case reportN. Bouattour0W. Bouattour1N. Messedi2F. Charfeddine3L. Aribi4J. Aloulou5Hedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, TunisiaHedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, TunisiaHedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, TunisiaHedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, TunisiaHedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, TunisiaHedi Chaker University Hospital Ain road 0.5 Km, Psychiatry B, Sfax, Tunisia Introduction Serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants thanks to the overall safety and tolerability spectrum. However, they can cause different side effects that not all of them are well identified. Objectives We intend to clarify the clinical presentation of mydriasis caused by Escitalopram. Methods Reporting the case of a patient suffering a major depressive disorder, that presented a mydriasis after adjusting her antidepressant medication. Then, we conducted a literature review using “PubMed” database and keywords “Mydriasis”, “escitalopram”, “SSRI”,” side effects”. Results A 29-year-old female with no past clinical history, presented in May 2021 a severe depression requiring an antidepressant treatment. Under 10 mg per day of escitalopram there was a partial remission of the symptoms, leading to increase the dose by another 10 mg. One month after taking 20 mg/day, she consults before the appointment suffering from a blurry vision and photophobia. Ophthalmologic examination showed a bilateral reactive half-mydriasis, eye pressure was 14 mmHg and fundus examination was normal. Iatrogenic origin of mydriasis was suspected. A gradual interruption of the medication lead to disappearance of the latter. A pharmacological investigation concluded to the suspension of escitalopram and to be vigilant if antidepressant medication would be needed. Conclusions Mydriasis is an uncommon side effect caused by SSRI that needs to be kept in mind by clinicians. Therapeutic patient education can help to detect abnormal side effects and treat them if needed. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822018788/type/journal_articlemydriasisescitalopramSide effectsSSRI |
| spellingShingle | N. Bouattour W. Bouattour N. Messedi F. Charfeddine L. Aribi J. Aloulou Mydriasis caused by ESCITALOPRAM: Case report European Psychiatry mydriasis escitalopram Side effects SSRI |
| title | Mydriasis caused by ESCITALOPRAM: Case report |
| title_full | Mydriasis caused by ESCITALOPRAM: Case report |
| title_fullStr | Mydriasis caused by ESCITALOPRAM: Case report |
| title_full_unstemmed | Mydriasis caused by ESCITALOPRAM: Case report |
| title_short | Mydriasis caused by ESCITALOPRAM: Case report |
| title_sort | mydriasis caused by escitalopram case report |
| topic | mydriasis escitalopram Side effects SSRI |
| url | https://www.cambridge.org/core/product/identifier/S0924933822018788/type/journal_article |
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