A retro-inverso cell-penetrating peptide for siRNA delivery

A retro-inverso cell-penetrating peptide for siRNA delivery

Abstract Background Small interfering RNAs (siRNAs) are powerful tools to control gene expression. However, due to their poor cellular permeability and stability, their therapeutic development requires a specific delivery system. Among them, cell-penetrating peptides (CPP) have been shown to transfe...

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Bibliographic Details
Main Authors: Anaïs Vaissière, Gudrun Aldrian, Karidia Konate, Mattias F. Lindberg, Carole Jourdan, Anthony Telmar, Quentin Seisel, Frédéric Fernandez, Véronique Viguier, Coralie Genevois, Franck Couillaud, Prisca Boisguerin, Sébastien Deshayes
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Journal of Nanobiotechnology
Subjects:
Enantiomer
d-Amino acids
Retro-inverso
siRNA delivery
Cell penetrating peptides
Nanoparticle
Online Access:http://link.springer.com/article/10.1186/s12951-017-0269-2

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