The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase

Human xanthine oxidoreductase (XOR) is a multilevel regulated enzyme, which has many physiological functions, but which is also involved in several pathological processes. The contributions of Stirpe and his research group at the University of Bologna, to the development of knowledge on the XOR enzy...

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Main Authors: Maria Giulia Battelli, Massimo Bortolotti, Letizia Polito, Andrea Bolognesi
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Advances in Redox Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667137922000273
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author Maria Giulia Battelli
Massimo Bortolotti
Letizia Polito
Andrea Bolognesi
author_facet Maria Giulia Battelli
Massimo Bortolotti
Letizia Polito
Andrea Bolognesi
author_sort Maria Giulia Battelli
collection DOAJ
description Human xanthine oxidoreductase (XOR) is a multilevel regulated enzyme, which has many physiological functions, but which is also involved in several pathological processes. The contributions of Stirpe and his research group at the University of Bologna, to the development of knowledge on the XOR enzyme and its implications in physiological and pathological processes made a breakthrough in this field. Furthermore, their pioneering results paved the way for many research lines that are still actual and that have relevant clinical implications.
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spelling doaj.art-d1543aab0cb741cca921b69edd8d42082023-03-14T04:09:10ZengElsevierAdvances in Redox Research2667-13792023-04-017100055The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductaseMaria Giulia Battelli0Massimo Bortolotti1Letizia Polito2Andrea Bolognesi3Department of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, ItalyDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, ItalyCorresponding author.; Department of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, ItalyDepartment of Experimental, Diagnostic and Specialty Medicine-DIMES, Alma Mater Studiorum, University of Bologna, ItalyHuman xanthine oxidoreductase (XOR) is a multilevel regulated enzyme, which has many physiological functions, but which is also involved in several pathological processes. The contributions of Stirpe and his research group at the University of Bologna, to the development of knowledge on the XOR enzyme and its implications in physiological and pathological processes made a breakthrough in this field. Furthermore, their pioneering results paved the way for many research lines that are still actual and that have relevant clinical implications.http://www.sciencedirect.com/science/article/pii/S2667137922000273GoutHyperuricemiaImmunotoxinsOxidative stressReactive oxygen speciesXanthine oxidoreductase
spellingShingle Maria Giulia Battelli
Massimo Bortolotti
Letizia Polito
Andrea Bolognesi
The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
Advances in Redox Research
Gout
Hyperuricemia
Immunotoxins
Oxidative stress
Reactive oxygen species
Xanthine oxidoreductase
title The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
title_full The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
title_fullStr The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
title_full_unstemmed The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
title_short The fundamental contribution of prof. Stirpe (and his research group) to the broadening of the scientific perspective on xanthine oxidoreductase
title_sort fundamental contribution of prof stirpe and his research group to the broadening of the scientific perspective on xanthine oxidoreductase
topic Gout
Hyperuricemia
Immunotoxins
Oxidative stress
Reactive oxygen species
Xanthine oxidoreductase
url http://www.sciencedirect.com/science/article/pii/S2667137922000273
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