Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy
Bladder cancer is one of the most common malignant tumors in urinary system. Intravesical chemotherapy is a common adjuvant therapy after transurethral resection of bladder tumors. However, it has several disadvantages such as low drug penetration rate, short residence time, unsustainable action and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.879828/full |
| _version_ | 1811245449352314880 |
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| author | Yilei Lu Siqi Wang Yuhang Wang Mingshan Li Yili Liu Dongwei Xue |
| author_facet | Yilei Lu Siqi Wang Yuhang Wang Mingshan Li Yili Liu Dongwei Xue |
| author_sort | Yilei Lu |
| collection | DOAJ |
| description | Bladder cancer is one of the most common malignant tumors in urinary system. Intravesical chemotherapy is a common adjuvant therapy after transurethral resection of bladder tumors. However, it has several disadvantages such as low drug penetration rate, short residence time, unsustainable action and inability to release slowly, thus new drug delivery and new modalities in delivery carriers need to be continuously explored. Nano-drug delivery system is a novel way in treatment for bladder cancer that can increase the absorption rate and prolong the duration of drug, as well as sustain the action by controlling drug release. Currently, nano-drug delivery carriers mainly included liposomes, polymers, and inorganic materials. In this paper, we reveal current researches in nano-drug delivery system in bladder cancer intravesical chemotherapy by describing the applications and defects of liposomes, polymers and inorganic material nanocarriers, and provide a basis for the improvement of intravesical chemotherapy drugs in bladder cancer. |
| first_indexed | 2024-04-12T14:39:17Z |
| format | Article |
| id | doaj.art-d157267f76404faeb063240a3949ed0d |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-12T14:39:17Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-d157267f76404faeb063240a3949ed0d2022-12-22T03:28:55ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-05-011210.3389/fonc.2022.879828879828Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical ChemotherapyYilei LuSiqi WangYuhang WangMingshan LiYili LiuDongwei XueBladder cancer is one of the most common malignant tumors in urinary system. Intravesical chemotherapy is a common adjuvant therapy after transurethral resection of bladder tumors. However, it has several disadvantages such as low drug penetration rate, short residence time, unsustainable action and inability to release slowly, thus new drug delivery and new modalities in delivery carriers need to be continuously explored. Nano-drug delivery system is a novel way in treatment for bladder cancer that can increase the absorption rate and prolong the duration of drug, as well as sustain the action by controlling drug release. Currently, nano-drug delivery carriers mainly included liposomes, polymers, and inorganic materials. In this paper, we reveal current researches in nano-drug delivery system in bladder cancer intravesical chemotherapy by describing the applications and defects of liposomes, polymers and inorganic material nanocarriers, and provide a basis for the improvement of intravesical chemotherapy drugs in bladder cancer.https://www.frontiersin.org/articles/10.3389/fonc.2022.879828/fullbladder cancerintravesical chemotherapynano-drug delivery systemliposomespolymersinorganic material |
| spellingShingle | Yilei Lu Siqi Wang Yuhang Wang Mingshan Li Yili Liu Dongwei Xue Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy Frontiers in Oncology bladder cancer intravesical chemotherapy nano-drug delivery system liposomes polymers inorganic material |
| title | Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy |
| title_full | Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy |
| title_fullStr | Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy |
| title_full_unstemmed | Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy |
| title_short | Current Researches on Nanodrug Delivery Systems in Bladder Cancer Intravesical Chemotherapy |
| title_sort | current researches on nanodrug delivery systems in bladder cancer intravesical chemotherapy |
| topic | bladder cancer intravesical chemotherapy nano-drug delivery system liposomes polymers inorganic material |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.879828/full |
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