Management and Therapeutic Options for COVID-19: A Review
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative organism for Coronavirus Disease 2019 (COVID-19), originated in Wuhan, China and has now spread to most parts of the world. A pandemic of this magnitude has not been witnessed in more than 100 years since the Spanish flu i...
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| Format: | Article |
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JCDR Research and Publications Private Limited
2020-11-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/14233/46071_CE[Ra1]_F(SL)_PF1(AG_SL)_PFA(KM)_PB(AG_Ss_KM)_PN(SL).pdf |
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| author | Karan Sachdeva Mradul Kumar Daga Govind Mawari Vijay Kumar Karra Naresh Kumar Sandeep Garg |
| author_facet | Karan Sachdeva Mradul Kumar Daga Govind Mawari Vijay Kumar Karra Naresh Kumar Sandeep Garg |
| author_sort | Karan Sachdeva |
| collection | DOAJ |
| description | Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative organism for Coronavirus Disease 2019 (COVID-19),
originated in Wuhan, China and has now spread to most parts of the world. A pandemic of this magnitude has not been witnessed
in more than 100 years since the Spanish flu in 1918. The major challenge for scientists and doctors worldwide has been to find a
therapeutic intervention to prevent the spread and development of this disease. As more research is being done, the pathophysiology
of COVID-19 has been explained, although no effective therapy has been found. Multiple drugs and therapies are under trials and a few
have shown inconclusive results. The attempts have ranged from repurposing drugs to trying to develop new vaccines. Formulation
of guidelines pose another challenge to the government and international agencies owing to the lack of data. These agencies have
constantly released and updated guidelines based on new research and growing knowledge. In this review, we aim to compare and
bring out the different international guidelines for management of COVID-19, along with a review of tried therapeutic interventions and
their primitive results. The COVID-19 has been a major global health crisis that is overpowering most heath care systems and multiple
agencies and research teams are trying to limit and manage this spread. Currently no effective treatment is available and guidelines
differ regarding the drugs that can be used, which are mostly off-label. |
| first_indexed | 2024-12-22T15:36:14Z |
| format | Article |
| id | doaj.art-d15b97923c494c9a8755c07c91c4b9b5 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-22T15:36:14Z |
| publishDate | 2020-11-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-d15b97923c494c9a8755c07c91c4b9b52022-12-21T18:21:15ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-11-011411OE01OE0810.7860/JCDR/2020/46071.14233Management and Therapeutic Options for COVID-19: A ReviewKaran Sachdeva0Mradul Kumar Daga1Govind Mawari2Vijay Kumar Karra3 Naresh Kumar4Sandeep Garg5MBBS Student, Maulana Azad Medical College, New Delhi, India.Director Professor, Department of Medicine and Center for Occupational and Environmental Health, Maulana Azad Medical College, New Delhi, India.Scientist B, Department of Medicine and Center for Occupational and Environmental Health, Maulana Azad Medical College, New Delhi, India.Scientist B, Department of Health Research, Division of Epidemiology and Communicable Diseases, Indian Council of Medical Research, New Delhi, India.Professor, Department of Medicine, Maulana Azad Medical College, New Delhi, India.Professor, Department of Medicine, Maulana Azad Medical College, New Delhi, India.Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the causative organism for Coronavirus Disease 2019 (COVID-19), originated in Wuhan, China and has now spread to most parts of the world. A pandemic of this magnitude has not been witnessed in more than 100 years since the Spanish flu in 1918. The major challenge for scientists and doctors worldwide has been to find a therapeutic intervention to prevent the spread and development of this disease. As more research is being done, the pathophysiology of COVID-19 has been explained, although no effective therapy has been found. Multiple drugs and therapies are under trials and a few have shown inconclusive results. The attempts have ranged from repurposing drugs to trying to develop new vaccines. Formulation of guidelines pose another challenge to the government and international agencies owing to the lack of data. These agencies have constantly released and updated guidelines based on new research and growing knowledge. In this review, we aim to compare and bring out the different international guidelines for management of COVID-19, along with a review of tried therapeutic interventions and their primitive results. The COVID-19 has been a major global health crisis that is overpowering most heath care systems and multiple agencies and research teams are trying to limit and manage this spread. Currently no effective treatment is available and guidelines differ regarding the drugs that can be used, which are mostly off-label.https://jcdr.net/articles/PDF/14233/46071_CE[Ra1]_F(SL)_PF1(AG_SL)_PFA(KM)_PB(AG_Ss_KM)_PN(SL).pdfacute respiratory distress syndromecoronavirus disease 2019hydroxychloroquinesevere acute respiratory syndrome coronavirus 2world health organisation |
| spellingShingle | Karan Sachdeva Mradul Kumar Daga Govind Mawari Vijay Kumar Karra Naresh Kumar Sandeep Garg Management and Therapeutic Options for COVID-19: A Review Journal of Clinical and Diagnostic Research acute respiratory distress syndrome coronavirus disease 2019 hydroxychloroquine severe acute respiratory syndrome coronavirus 2 world health organisation |
| title | Management and Therapeutic Options for COVID-19: A Review |
| title_full | Management and Therapeutic Options for COVID-19: A Review |
| title_fullStr | Management and Therapeutic Options for COVID-19: A Review |
| title_full_unstemmed | Management and Therapeutic Options for COVID-19: A Review |
| title_short | Management and Therapeutic Options for COVID-19: A Review |
| title_sort | management and therapeutic options for covid 19 a review |
| topic | acute respiratory distress syndrome coronavirus disease 2019 hydroxychloroquine severe acute respiratory syndrome coronavirus 2 world health organisation |
| url | https://jcdr.net/articles/PDF/14233/46071_CE[Ra1]_F(SL)_PF1(AG_SL)_PFA(KM)_PB(AG_Ss_KM)_PN(SL).pdf |
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