Population Genetics of the European Roma—A Review
The Roma are a group of populations with a common origin that share the Romani identity and cultural heritage. Their genetic history has been inferred through multiple studies based on uniparental and autosomal markers, and current genomic data have provided novel insights into their genetic backgro...
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MDPI AG
2022-11-01
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Series: | Genes |
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Online Access: | https://www.mdpi.com/2073-4425/13/11/2068 |
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author | Giacomo Francesco Ena Julen Aizpurua-Iraola Neus Font-Porterias Francesc Calafell David Comas |
author_facet | Giacomo Francesco Ena Julen Aizpurua-Iraola Neus Font-Porterias Francesc Calafell David Comas |
author_sort | Giacomo Francesco Ena |
collection | DOAJ |
description | The Roma are a group of populations with a common origin that share the Romani identity and cultural heritage. Their genetic history has been inferred through multiple studies based on uniparental and autosomal markers, and current genomic data have provided novel insights into their genetic background. This review was prompted by two factors: (i) new developments to estimate the genetic structure of the Roma at a fine-scale resolution have precisely identified the ancestral components and traced migrations that were previously documented only in historical sources, clarifying and solving debates on the origins and the diaspora of the Roma; (ii) while there has been an effort to review the health determinants of the Roma, the increasing literature on their population genetics has not been subjected to a dedicated review in the last two decades. We believe that a summary on the state of the art will benefit both the public and scholars that are approaching the subject. |
first_indexed | 2024-03-09T19:03:55Z |
format | Article |
id | doaj.art-d15beee1fa534ff3842abdcefe28dc7e |
institution | Directory Open Access Journal |
issn | 2073-4425 |
language | English |
last_indexed | 2024-03-09T19:03:55Z |
publishDate | 2022-11-01 |
publisher | MDPI AG |
record_format | Article |
series | Genes |
spelling | doaj.art-d15beee1fa534ff3842abdcefe28dc7e2023-11-24T04:49:16ZengMDPI AGGenes2073-44252022-11-011311206810.3390/genes13112068Population Genetics of the European Roma—A ReviewGiacomo Francesco Ena0Julen Aizpurua-Iraola1Neus Font-Porterias2Francesc Calafell3David Comas4Department of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, SpainDepartment of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, SpainDepartment of Biomedical Informatics, Anschutz Medical Campus, University of Colorado, Aurora, CO 80309, USADepartment of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, SpainDepartment of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, SpainThe Roma are a group of populations with a common origin that share the Romani identity and cultural heritage. Their genetic history has been inferred through multiple studies based on uniparental and autosomal markers, and current genomic data have provided novel insights into their genetic background. This review was prompted by two factors: (i) new developments to estimate the genetic structure of the Roma at a fine-scale resolution have precisely identified the ancestral components and traced migrations that were previously documented only in historical sources, clarifying and solving debates on the origins and the diaspora of the Roma; (ii) while there has been an effort to review the health determinants of the Roma, the increasing literature on their population genetics has not been subjected to a dedicated review in the last two decades. We believe that a summary on the state of the art will benefit both the public and scholars that are approaching the subject.https://www.mdpi.com/2073-4425/13/11/2068population geneticsgenomicsRomanigenetic structurebottleneckfounder event |
spellingShingle | Giacomo Francesco Ena Julen Aizpurua-Iraola Neus Font-Porterias Francesc Calafell David Comas Population Genetics of the European Roma—A Review Genes population genetics genomics Romani genetic structure bottleneck founder event |
title | Population Genetics of the European Roma—A Review |
title_full | Population Genetics of the European Roma—A Review |
title_fullStr | Population Genetics of the European Roma—A Review |
title_full_unstemmed | Population Genetics of the European Roma—A Review |
title_short | Population Genetics of the European Roma—A Review |
title_sort | population genetics of the european roma a review |
topic | population genetics genomics Romani genetic structure bottleneck founder event |
url | https://www.mdpi.com/2073-4425/13/11/2068 |
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