Validating Enteroid-Derived Monolayers from Murine Gut Organoids for Toxicological Testing of Inorganic Particles: Proof-of-Concept with Food-Grade Titanium Dioxide

Validating Enteroid-Derived Monolayers from Murine Gut Organoids for Toxicological Testing of Inorganic Particles: Proof-of-Concept with Food-Grade Titanium Dioxide

Human exposure to foodborne inorganic nanoparticles (NPs) is a growing concern. However, identifying potential hazards linked to NP ingestion often requires long-term exposure in animals. Owing these constraints, intestinal organoids are a promising alternative to in vivo experiments; as such, an in...

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Bibliographic Details
Main Authors: Yann Malaisé, Eva Casale, Aurélie Pettes-Duler, Christel Cartier, Eric Gaultier, Natalia Martins Breyner, Eric Houdeau, Lauris Evariste, Bruno Lamas
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
intestinal organoids
toxicity testing
food toxicology
inorganic particles
food additive titanium dioxide
Online Access:https://www.mdpi.com/1422-0067/25/5/2635

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