Glycolysis Inhibition of Autophagy Drives Malignancy in Ovarian Cancer: Exacerbation by IL-6 and Attenuation by Resveratrol

Glycolysis Inhibition of Autophagy Drives Malignancy in Ovarian Cancer: Exacerbation by IL-6 and Attenuation by Resveratrol

Cancer cells drive the glycolytic process towards the fermentation of pyruvate into lactate even in the presence of oxygen and functioning mitochondria, a phenomenon known as the “Warburg effect”. Although not energetically efficient, glycolysis allows the cancer cell to synthesize the metabolites n...

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Bibliographic Details
Main Authors: Chiara Vidoni, Alessandra Ferraresi, Letizia Vallino, Amreen Salwa, Ji Hee Ha, Christian Seca, Beatrice Garavaglia, Danny N. Dhanasekaran, Ciro Isidoro
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Warburg effect
glycolysis
ovarian cancer
hexokinase 2
nutraceuticals
pro-inflammatory cytokines
Online Access:https://www.mdpi.com/1422-0067/24/2/1723

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