Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway

Grb2 Induces Cardiorenal Syndrome Type 3: Roles of IL-6, Cardiomyocyte Bioenergetics, and Akt/mTOR Pathway

Cardiorenal syndrome type 3 (CRS-3) is damage to the heart following acute kidney injury (AKI). Although many experiments have found that inflammation, oxidative stress, and cardiomyocyte death are involved in cardiomyocyte pathophysiological alterations during CRS-3, they lack a non-bias analysis t...

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Bibliographic Details
Main Authors: Jin Wang, Xuefeng Sun, Xu Wang, Shaoyuan Cui, Ran Liu, Jiaona Liu, Bo Fu, Ming Gong, Conghui Wang, Yushen Shi, Qianqian Chen, Guangyan Cai, Xiangmei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CRS-3
GRB2
cardiomyocytes
kidney
mitochondria
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.630412/full

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