Biologic Abatement and Capturing Kids’ Outcomes and Flare Frequency in Juvenile Spondyloarthritis (BACK-OFF JSpA): study protocol for a randomized pragmatic trial

Abstract Background The effectiveness of biologic therapies, primarily tumor necrosis factor inhibitors (TNFi), for children with spondyloarthritis (SpA) has made inactive disease a realistic patient outcome. However, biologic therapies are costly, primarily delivered by subcutaneous or intravenous...

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Hlavní autoři: Pamela F. Weiss, Cora E. Sears, Timothy G. Brandon, Christopher B. Forrest, Emily Neu, Melanie Kohlheim, Jenny Leal, Rui Xiao, Daniel Lovell
Médium: Článek
Jazyk:English
Vydáno: BMC 2023-02-01
Edice:Trials
Témata:
On-line přístup:https://doi.org/10.1186/s13063-022-07038-6