EFFICACY OF POTENTIAL ATYPICAL ANTIPSYCHOTIC LEK-8829 ON BEHAVIORAL EFFECTS IN RAT MODEL OF CATALEPSY AND INHIBITION OF AMPHETAMINE INDUCED PSYCHOMOTOR STIMULATION
D2 antagonist drugs, such as haloperidol, are potent antipsychotic drugs but unfortunately also have a high propensity to cause unwanted extrapyramidal syndrome (EPS). LEK-8829 is a dopamine D2 receptor antagonist with intrinsic activity at dopamine D1 receptors. Here we speculate that the intrinsic...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
University of Ljubljana Press (Založba Univerze v Ljubljani)
2015-06-01
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| Series: | Slovenian Veterinary Research |
| Online Access: | https://www.slovetres.si/index.php/SVR/article/view/79 |